ArticleJournal of agricultural and food chemistry2015
Structural Characterization of Melanin Pigments from Commercial Preparations of the Edible Mushroom Auricularia auricula.
Article in Journal of agricultural and food chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 83 citations in OpenAlex.
- Microbial production of eumelanin from a desert-derived Aspergillus terreus: statistical optimization, comprehensive characterization, and in silico insights into breast cancer-associated targets.Microbial cell factories · 2026Article
- Photoregulation of the biosynthetic activity of fungusBioengineered · 2025Article
- Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications.Journal of fungi (Basel, Switzerland) · 2025Review
- Genetic, structural, and functional characterization of allomelanin from black yeast Exophiala viscosa, a chassis for fungal melanin production.Applied microbiology and biotechnology · 2025Article
- Isolation and Structural Characterization of Melanins from Red and Yellow Varieties ofInternational journal of molecular sciences · 2025Article
- Article
- Regulation of melanin production in fungi.Frontiers in fungal biology · 2025Review
- Basidiomycete pigments as sustainable food colorants and stabilizers: from fungal biology to industrial potential.Frontiers in microbiology · 2025Review
- Transcriptom Analysis ofMycobiology · 2025Article
- Melanin in fungi: advances in structure, biosynthesis, regulation, and metabolic engineering.Microbial cell factories · 2024Review
- Biocompatible melanin from the marine black yeast Hortaea werneckii R23 with antioxidant and photoprotection property.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- Melanin inFood science and biotechnology · 2024Review
- Date fruit melanin is primarily based on (-)-epicatechin proanthocyanidin oligomers.Scientific reports · 2024Article
- Bioproduction and optimization of newly characterized melanin pigment from Streptomyces djakartensis NSS-3 with its anticancer, antimicrobial, and radioprotective properties.Microbial cell factories · 2024Article
- Characterization and Biological Activities of Melanin from the Medicinal FungiInternational journal of molecular sciences · 2023Article
- Fungi as a source of eumelanin: current understanding and prospects.Journal of industrial microbiology & biotechnology · 2023Article
- Rapid, high-titer biosynthesis of melanin using the marine bacteriumFrontiers in bioengineering and biotechnology · 2023Article
- Synthesis and structural characteristics analysis of melanin pigments induced by blue light inFrontiers in microbiology · 2023Article
- Production of Fungal Pigments: Molecular Processes and Their Applications.Journal of fungi (Basel, Switzerland) · 2022Review
- Melanin of fungi: from classification to application.World journal of microbiology & biotechnology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Many of the most widely consumed edible mushrooms are pigmented, and these have been associated with some beneficial health effects. Nevertheless, the majority of the reported compounds associated with these desirable properties are non-pigmented. We have previously reported that melanin pigment from the edible mushroom Auricularia auricula can protect mice against ionizing radiation, although no physicochemical characterization was reported. Consequently, in this study we have characterized commercial A. auricula mushroom preparations for melanin content and carried out structural characterization of isolated insoluble melanin materials using a panel of sophisticated spectroscopic and physical/imaging techniques. Our results show that approximately 10% of the dry mass of A. auricula is melanin and that the pigment has physicochemical properties consistent with those of eumelanins, including hosting a stable free radical population. Electron microscopy studies show that melanin is associated with the mushroom cell wall in a manner similar to that of melanin from the model fungus C. neoformans. Elemental analysis of melanin indicated C, H, and N ratios consistent with 5,6-dihydroxyindole-2-carboxylic acid/5,6-dihydroxyindole and 1,8-dihydroxynaphthalene eumelanin. Validation of the identity of the isolated product as melanin was achieved by EPR analysis. A. auricula melanin manifested structural differences, relative to the C. neoformans melanin, with regard to the variable proportions of alkyl chains or oxygenated carbons. Given the necessity for new oral and inexpensive radioprotective materials coupled with the commercial availability of A. auricula mushrooms, this product may represent an excellent source of edible melanin.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.