Evidence map›Paper›PMID 26244060›Full record

ArticleMobile DNA2015

A call for benchmarking transposable element annotation methods.

Douglas R Hoen, Glenn Hickey, Guillaume Bourque, Josep Casacuberta, Richard Cordaux, Cédric Feschotte, Anna-Sophie Fiston-Lavier, Aurélie Hua-Van, Robert Hubley, Aurélie Kapusta and 8 more

Open access · goldAbstract read
In one paragraph

Article in Mobile DNA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 98 citations in OpenAlex.

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  17. Finding and Characterizing Repeats in Plant Genomes.Methods in molecular biology (Clifton, N.J.) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 4 countries.

Douglas R HoenSchool of Computer Science, McGill University, McConnell Engineering Bldg., Rm. 318, 3480 Rue University, Montréal, Québec H3A 0E9 Canada ; Department of Biology, McGill University, Stewart Biology Bldg., 1205 Ave. du Docteur-Penfield, Montréal, Québec H3A 1B1 Canada.
Glenn HickeySchool of Computer Science, McGill University, McConnell Engineering Bldg., Rm. 318, 3480 Rue University, Montréal, Québec H3A 0E9 Canada ; McGill Centre for Bioinformatics, McGill University, Montréal, Québec Canada.
Guillaume BourqueDepartment of Human Genetics, McGill University, Montréal, Québec Canada ; McGill University and Génome Québec Innovation Center, Montréal, Québec Canada.
Josep CasacubertaCentre for Research in Agricultural Genomics CSIC-IRTA-UAB-UB, 08193 Barcelona, Spain.
Richard CordauxUniversité de Poitiers, UMR CNRS 7267 Ecologie et Biologie des Interactions, Equipe Ecologie Evolution Symbiose, 5 Rue Albert Turpin, 86073 Poitiers Cedex 9, France.
Cédric FeschotteDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112 USA.
Anna-Sophie Fiston-LavierInstitut des Sciences de l'Evolution de Montpellier (ISE-M), Equipe Evolution, Vecteurs, Adaptation et Symbiose, UMR5554 CNRS-Université Montpellier, Montpellier, 34090 cedex 05 France.
Aurélie Hua-VanLaboratoire Evolution, Génomes, Comportement Ecologie, CNRS-Université Paris-Sud (UMR 9191)-IRD (UMR 247)-Université Paris-Saclay, F-91198 Gif-sur-Yvette, France.
Robert HubleyInstitute for Systems Biology, 401 Terry Ave. N, Seattle, WA 98109 USA.
Aurélie KapustaDepartment of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112 USA.
Emmanuelle LeratLaboratoire Biometrie et Biologie Evolutive, Universite Claude Bernard-Lyon 1, UMR-CNRS 5558-Bat. Mendel, 43 bd du 11 novembre 1918, 69622 Villeurbanne cedex, France.
Florian MaumusINRA, UR1164 URGI-Research Unit in Genomics-Info, INRA de Versailles-Grignon, Route de Saint-Cyr, Versailles, 78026 France.
David D PollockUniversity of Colorado School of Medicine, Aurora, CO 80045 USA.
Hadi QuesnevilleINRA, UR1164 URGI-Research Unit in Genomics-Info, INRA de Versailles-Grignon, Route de Saint-Cyr, Versailles, 78026 France.
Arian SmitInstitute for Systems Biology, 401 Terry Ave. N, Seattle, WA 98109 USA.
Travis J WheelerDepartment of Computer Science, University of Montana, Missoula, MT 59812 USA.
Thomas E BureauDepartment of Biology, McGill University, Stewart Biology Bldg., 1205 Ave. du Docteur-Penfield, Montréal, Québec H3A 1B1 Canada.
Mathieu BlanchetteSchool of Computer Science, McGill University, McConnell Engineering Bldg., Rm. 318, 3480 Rue University, Montréal, Québec H3A 0E9 Canada ; McGill Centre for Bioinformatics, McGill University, Montréal, Québec Canada.
McGill University · CACentre National de la Recherche Scientifique · FRInstitute for Systems Biology · USUniversity of Utah · USCenter for Research in Agricultural Genomics · ESUniversité de Montpellier · FRUniversité Paris-Sud · FRUniversity of Colorado Denver · USUniversity of Montana · US

Funding

Maintenance and Development of RepeatMasker and RepeatModelerR01HG002939 · NHGRI · INSTITUTE FOR SYSTEMS BIOLOGY · PI Robert MacDonald Hubley, Arian Fredericus Anthonius Smit · 2003 to 2026
$9.1M
Human DNA transposons: evolutionary history and genomic impactR01GM077582 · NIGMS · UNIVERSITY OF UTAH · PI FESCHOTTE, CEDRIC · 2007 to 2015
$1.4M
Genome-wide mutation models to decipher functionR01GM097251 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI POLLOCK, DAVID D · 2012 to 2015
$1.2M
NHGRI NIH HHS R01 HG002939NIGMS NIH HHS R01 GM077582NIGMS NIH HHS R01 GM097251
6 · The paper itself

Abstract

DNA derived from transposable elements (TEs) constitutes large parts of the genomes of complex eukaryotes, with major impacts not only on genomic research but also on how organisms evolve and function. Although a variety of methods and tools have been developed to detect and annotate TEs, there are as yet no standard benchmarks-that is, no standard way to measure or compare their accuracy. This lack of accuracy assessment calls into question conclusions from a wide range of research that depends explicitly or implicitly on TE annotation. In the absence of standard benchmarks, toolmakers are impeded in improving their tools, annotators cannot properly assess which tools might best suit their needs, and downstream researchers cannot judge how accuracy limitations might impact their studies. We therefore propose that the TE research community create and adopt standard TE annotation benchmarks, and we call for other researchers to join the authors in making this long-overdue effort a success.

Identifiers

PMID26244060
PMCPMC4524446
OpenAlexW1680689267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.