ArticleProceedings of the National Academy of Sciences of the United States of America2015
Heterochrony underpins natural variation in Cardamine hirsuta leaf form.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- New components in genetic regulation of age-dependent compound leaf architecture in pea.The New phytologist · 2026Article
- Heterochronic shifts in a timing-keeping microRNA are associated with multiple instances of neoteny in plants.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The trichome pattern diversity of Cardamine shares genetic mechanisms with Arabidopsis but differs in environmental drivers.Plant physiology · 2024Article
- FLOWERING LOCUS T-mediated thermal signalling regulates age-dependent inflorescence development in Arabidopsis thaliana.Journal of experimental botany · 2024Article
- Topological data analysis reveals core heteroblastic and ontogenetic programs embedded in leaves of grapevine (Vitaceae) and maracuyá (Passifloraceae).PLoS computational biology · 2024Article
- Evolutionary Dynamics ofPlants (Basel, Switzerland) · 2023Article
- Pan-European study of genotypes and phenotypes in the Arabidopsis relative Cardamine hirsuta reveals how adaptation, demography, and development shape diversity patterns.PLoS biology · 2023Article
- Leaf Development inGenes · 2022Review
- The VIL gene CRAWLING ELEPHANT controls maturation and differentiation in tomato via polycomb silencing.PLoS genetics · 2022Article
- Article
- Gene regulatory networks controlled by FLOWERING LOCUS C that confer variation in seasonal flowering and life history.Journal of experimental botany · 2021Article
- The Diverse Roles of FLOWERING LOCUS C in Annual and Perennial Brassicaceae Species.Frontiers in plant science · 2021Review
- Plant science's next top models.Annals of botany · 2020Review
- CRISPR/Cas9-Mediated Mutagenesis ofPlants (Basel, Switzerland) · 2020Article
- A spatiotemporally regulated transcriptional complex underlies heteroblastic development of leaf hairs inThe EMBO journal · 2019Article
- The role ofeLife · 2018Article
- An Ultrahigh-Dimensional Mapping Model of High-order Epistatic Networks for Complex Traits.Current genomics · 2018Article
- Why are the seed cones of conifers so diverse at pollination?Annals of botany · 2018Article
- Mechanisms Underlying the Environmentally Induced Plasticity of Leaf Morphology.Frontiers in genetics · 2018Review
- MowJoe: a method for automated-high throughput dissected leaf phenotyping.Plant methods · 2018Article
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9 authors.
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Abstract
A key problem in biology is whether the same processes underlie morphological variation between and within species. Here, by using plant leaves as an example, we show that the causes of diversity at these two evolutionary scales can be divergent. Some species like the model plant Arabidopsis thaliana have simple leaves, whereas others like the A. thaliana relative Cardamine hirsuta bear complex leaves comprising leaflets. Previous work has shown that these interspecific differences result mostly from variation in local tissue growth and patterning. Now, by cloning and characterizing a quantitative trait locus (QTL) for C. hirsuta leaf shape, we find that a different process, age-dependent progression of leaf form, underlies variation in this trait within species. This QTL effect is caused by cis-regulatory variation in the floral repressor ChFLC, such that genotypes with low-expressing ChFLC alleles show both early flowering and accelerated age-dependent changes in leaf form, including faster leaflet production. We provide evidence that this mechanism coordinates leaf development with reproductive timing and may help to optimize resource allocation to the next generation.
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