Evidence map›Paper›PMID 26243623›Full record

ReviewInternational journal of hematology2015

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) after treatment for Hodgkin's lymphoma.

Kyoko Mashima, Shigeaki Suzuki, Takehiko Mori, Toshihiko Shimizu, Satoshi Yamada, Shigemichi Hirose, Shinichiro Okamoto, Norihiro Suzuki

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in International journal of hematology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Brain biopsy in patients with CLIPPERS syndrome: why and when.Therapeutic advances in neurological disorders · 2022
    Article
  3. Review
  4. Article
  5. Article
  6. CLIPPERS.Current neurology and neuroscience reports · 2017
    Review
  7. Therapeutic Approaches in CLIPPERS.Current treatment options in neurology · 2017
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kyoko MashimaDepartment of Neurology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. k-mash.1992@live.jp.
Shigeaki SuzukiDepartment of Neurology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. sgsuzuki@z3.keio.jp.
Takehiko MoriDivision of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan. tmori@a3.keio.jp.
Toshihiko ShimizuDepartment of Neurology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. shimizu-toshi@umin.ac.jp.
Satoshi YamadaDepartment of Neurology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. ymd.jan.88@image.ocn.ne.jp.
Shigemichi HiroseDivision of Diagnostic Pathology, Keio University School of Medicine, Tokyo, Japan. shirose1231@gmail.com.
Shinichiro OkamotoDivision of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan. okamoto@a7.keio.jp.
Norihiro SuzukiDepartment of Neurology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan. nrsuzuki@a2.keio.jp.
Keio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a rare central nervous system (CNS) disorder with distinct radiological features. However, CLIPPERS may mimic CNS lymphoma, and several cases in which CLIPPERS occurred premonitory to CNS lymphoma have been reported. We report a 31-year-old man presenting with progressive gait ataxia and the characteristic MRI features of CLIPPERS. He was diagnosed with stage II Hodgkin's lymphoma at the age of 15, and we considered the possibility of newly emerged CNS lymphoma occurring in the immunosuppressive condition after the treatment of Hodgkin's lymphoma. Histological findings showed no evidence of CNS lymphoma and the neurological symptoms were resolved by steroids. Although CLIPPERS developed in the reverse order in this case, CLIPPERS should be considered in different diagnosis for CNS lymphoma.

Indexed as

AdultAntineoplastic Combined Chemotherapy ProtocolsBiopsyCentral Nervous System NeoplasmsChronic DiseaseCyclophosphamideDiagnosis, DifferentialEncephalitisHodgkin DiseaseHumansMagnetic Resonance ImagingMaleNeuroimagingPonsPrednisolonePrednisoneCyclophosphamidePrednisolonePrednisoneProcarbazineVincristineBrain biopsyCLIPPERSCNS lymphomaMRI

Identifiers

PMID26243623
OpenAlexW1051351336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.