Evidence map›Paper›PMID 26242817›Full record

ReviewTrends in endocrinology and metabolism: TEM2015

Metabolomic profiling of hormone-dependent cancers: a bird's eye view.

Stacy M Lloyd, James Arnold, Arun Sreekumar

Abstract readReview
In one paragraph

Review in Trends in endocrinology and metabolism: TEM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. The Heterogeneity of Breast Cancer Metabolism.Advances in experimental medicine and biology · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Vitamins, metabolomics, and prostate cancer.World journal of urology · 2017
    Article
  16. Article
  17. Review
  18. Review
  19. Scientific reports · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stacy M LloydAlkek Center for Molecular Discovery, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
James ArnoldAlkek Center for Molecular Discovery, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
Arun SreekumarAlkek Center for Molecular Discovery, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: arun.sreekumar@bcm.edu.

Funding

METABOLOMIC PROFILING AND BIOLOGIC BASIS OF RACIAL DISPARITY IN PROSTATE CANCERU01CA167234 · NCI · BAYLOR COLLEGE OF MEDICINE · PI PALAPATTU, GANESH S, SREEKUMAR, ARUN · 2012 to 2016
$1.9M
Delineating racially distinct metabolic pathways in triple negative breast cancerU01CA179674 · NCI · BAYLOR COLLEGE OF MEDICINE · PI SREEKUMAR, ARUN · 2014 to 2018
$1.7M
High Kynurenine in Agressive Triple Negative African American Breast CancerR21CA185516 · NCI · BAYLOR COLLEGE OF MEDICINE · PI SREEKUMAR, ARUN · 2014 to 2015
$374k
NCI NIH HHS R21 CA185516NCI NIH HHS R21CA185516NCI NIH HHS U01 CA167234NCI NIH HHS U01CA167234NCI NIH HHS U01CA167234S1NCI NIH HHS U01 CA179674NCI NIH HHS U01CA179674
6 · The paper itself

Abstract

Hormone-dependent cancers present a significant public health challenge, because they are among the most common cancers in the world. One factor associated with cancer development and progression is metabolic reprogramming. By understanding these alterations, we can identify potential markers and novel biochemical therapeutic targets. Metabolic profiling is an advanced technology that allows investigators to assess low-molecular-weight compounds that reflect physiological alterations. Current research in metabolomics on prostate (PCa) and breast cancer (BCa) have made great strides in uncovering specific metabolic pathways that are associated with cancer development, progression, and resistance. In this review, we highlight some of the major findings and potential therapeutic advances that have been reported utilizing this technology.

Indexed as

HormonesMetabolomicsBiomarkers, TumorBreast NeoplasmsFemaleHumansMaleNeoplasmsProstatic NeoplasmsBiomarkers, TumorHormonesbiomarkersbreast cancermetabolomicsprostate cancertherapeutic targets

Identifiers

PMID26242817
PMCPMC4560106

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.