Evidence map›Paper›PMID 26242805›Full record

ArticleJournal of the American Society for Mass Spectrometry2015

Numerical analysis of ion-funnel transmission efficiency in an API-MS system with a continuum/microscopic approach.

Sergey Gimelshein, Taylor Lilly, Eugene Moskovets

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sergey GimelsheinUniversity of Southern California, Los Angeles, CA, 90089, USA. gimelshe@usc.edu.
Taylor LillyUniversity of Colorado at Colorado Springs, Colorado Springs, CO, 80918, USA.
Eugene MoskovetsMassTech, Inc., Colombia, MD, 21046, USA.

Funding

Fast fragmentation method for characterization of peptides with labile PTMsR43GM103358 · NIGMS · MASSTECH, INC. · PI MOSKOVETS, EUGENE · 2012 to 2012
$414k
NIGMS NIH HHS R43GM103358
6 · The paper itself

Abstract

A multi-step numerical approach is used to analyze the efficiency of an ion-funnel to transport ions over a wide range of m/z. A continuum approach based on the solution of the Navier-Stokes equations is applied to model the gas flow through a capillary connecting the atmospheric and subatmospheric sections of a mass spectrometer. A microscopic, fully kinetic approach based on the solution of the Boltzmann equation is used to examine the ion and gas transport through an ion-funnel kept at a 0.1-3 Torr pressure to the quadrupole section kept at a 0.01 Torr pressure. In addition to aerodynamic drag, the developed approach takes into account the combined effect of the DC field driving the ions downstream toward the funnel exit, the rf field confining the ions in radial direction, and the space charge causing ion repulsion. The sensitivity of the ion transmission to the gas pressure in the ion-funnel, the rf, and the total ion current injected to the funnel from capillary nozzle is shown. Graphical Abstract ᅟ.

Indexed as

Equipment DesignKineticsMicroscopyModels, TheoreticalPressureSpectrometry, Mass, Electrospray IonizationIon-funnelIon transmissionKinetic modeling

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.