Evidence map›Paper›PMID 26242774›Full record

ArticleForensic science, medicine, and pathology2015

Fatal laryngeal angioedema: a case report and a workup of angioedema in a forensic setting.

Adriana Krizova, Taylor Gardner, D'Arcy L Little, V Arcieri-Piersanti, Michael S Pollanen

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Forensic science, medicine, and pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Lethal manifestations of angioedema.Forensic science, medicine, and pathology · 2019
    Article
  4. Epidemiology of ACE Inhibitor Angioedema Utilizing a Large Electronic Health Record.The journal of allergy and clinical immunology. In practice
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adriana KrizovaOntario Forensic Pathology Service, Forensic Services and Coroner's Complex, Toronto, ON, Canada. Adriana.krizova@mail.utoronto.ca.
Taylor GardnerOntario Forensic Pathology Service, Forensic Services and Coroner's Complex, Toronto, ON, Canada.
D'Arcy L LittleOntario Forensic Pathology Service, Forensic Services and Coroner's Complex, Toronto, ON, Canada.
V Arcieri-PiersantiForensic Services and Coroner's Complex, Toronto, ON, Canada.
Michael S PollanenOntario Forensic Pathology Service, Forensic Services and Coroner's Complex, Toronto, ON, Canada.
Advantage Forensics (Canada) · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angioedema is an episodic swelling of the deep dermis, subcutis, and/or submucosal tissue due to an increase in local vascular permeability. Swelling may involve skin, respiratory, and gastrointestinal tracts. The most commonly involved areas are the periorbital region and the lips. Here we report a case of a fatal laryngeal obstruction due to angioedema likely caused by an angiotensin-converting-enzyme inhibitor. The decedent, a 58-year-old man, was witnessed developing sudden facial swelling and acute respiratory difficulties quickly followed by unresponsiveness. His past medical history suggested that this was his second episode of angioedema without urticaria. Postmortem examination revealed a complete laryngeal obstruction in the absence of infection, neoplasm, or autoimmune disease. Postmortem computed tomography of the head and neck showed a complete obstruction of the upper airway. Based on the current understanding of the pathophysiology of different types of angioedema, we will suggest a workup of angioedema without urticaria in the forensic setting and offer readers resources they can use in their practice.

Indexed as

Airway ObstructionAngioedemaAngiotensin-Converting Enzyme InhibitorsFatal OutcomeHumansLaryngeal DiseasesMaleMiddle AgedRadiographyAngiotensin-Converting Enzyme InhibitorsACEI induced angioedemaAngioedemaAngioedema workup in forensic pathologyDrug induced angioedemaPostmortem CT of angioedema

Identifiers

PMID26242774
OpenAlexW1066625123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.