Evidence map›Paper›PMID 26242725›Full record

ReviewEuropean journal of clinical nutrition2015

Body composition during fetal development and infancy through the age of 5 years.

T Toro-Ramos, C Paley, F X Pi-Sunyer, D Gallagher

Open access · greenAbstract readReview
In one paragraph

Review in European journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Influence of Prenatal Aerobic Exercise on Fetal Morphometry.Maternal and child health journal · 2020
    Trial
  7. Trial
  8. Trial
  9. Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. BMI profiling for monogenic obesity testing.The Lancet. Child & adolescent health · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

T Toro-RamosDepartment of Medicine, New York Obesity Nutrition Research Center, St Luke's-Roosevelt Hospital, New York, NY, USA.
C PaleyDepartment of Medicine, New York Obesity Nutrition Research Center, St Luke's-Roosevelt Hospital, New York, NY, USA.
F X Pi-SunyerDepartment of Medicine, New York Obesity Nutrition Research Center, St Luke's-Roosevelt Hospital, New York, NY, USA.
D GallagherDepartment of Medicine, New York Obesity Nutrition Research Center, St Luke's-Roosevelt Hospital, New York, NY, USA.
St. Luke's-Roosevelt Hospital Center · US

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Lifestyle Interventions in Overweight and Obese Pregnant WomenU01DK094463 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI GALLAGHER, DYMPNA, PI-SUNYER, XAVIER · 2011 to 2017
$5.3M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1-TR000040NIDDK NIH HHS P30 DK026687NIDDK NIH HHS P30-DK-26687NIDDK NIH HHS T32 DK007559NIDDK NIH HHS U01 DK094463NIDDK NIH HHS UO1-DK-094463
6 · The paper itself

Abstract

Fetal body composition is an important determinant of body composition at birth, and it is likely to be an important determinant at later stages in life. The purpose of this work is to provide a comprehensive overview by presenting data from previously published studies that report on body composition during fetal development in newborns and the infant/child through 5 years of age. Understanding the changes in body composition that occur both in utero and during infancy and childhood, and how they may be related, may help inform evidence-based practice during pregnancy and childhood. We describe body composition measurement techniques from the in utero period to 5 years of age, and identify gaps in knowledge to direct future research efforts. Available literature on chemical and cadaver analyses of fetal studies during gestation is presented to show the timing and accretion rates of adipose and lean tissues. Quantitative and qualitative aspects of fetal lean and fat mass accretion could be especially useful in the clinical setting for diagnostic purposes. The practicality of different pediatric body composition measurement methods in the clinical setting is discussed by presenting the assumptions and limitations associated with each method that may assist the clinician in characterizing the health and nutritional status of the fetus, infant and child. It is our hope that this review will help guide future research efforts directed at increasing the understanding of how body composition in early development may be associated with chronic diseases in later life.

Indexed as

Body CompositionChild DevelopmentFetal DevelopmentAdipose TissueBody Mass IndexChild, PreschoolEnergy IntakeFemaleHumansInfantMalePregnancy

Identifiers

PMID26242725
PMCPMC4680980
OpenAlexW2190936842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.