ArticleLeukemia2015
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.
Article in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- De novo variants in the splicing factor gene SF3B1 are associated with neurodevelopmental disorders.Nature communications · 2026Article
- Article
- Review
- ZetaSuite: computational analysis of two-dimensional high-throughput data from multi-target screens and single-cell transcriptomics.Genome biology · 2022Article
- Mutation in SF3B1 gene promotes formation of polyploid giant cells in Leukemia cells.Medical oncology (Northwood, London, England) · 2022Article
- The genetics of myelodysplastic syndromes and the opportunities for tailored treatments.Frontiers in oncology · 2022Review
- SF3B1 mutation in pancreatic cancer contributes to aerobic glycolysis and tumor growth through a PP2A-c-Myc axis.Molecular oncology · 2021Article
- Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers.Nature communications · 2020Article
- Spliceosomopathies: Diseases and mechanisms.Developmental dynamics : an official publication of the American Association of Anatomists · 2020Review
- Distinct mutational pattern of myelodysplastic syndromes with and without 5q- treated with lenalidomide.British journal of haematology · 2020Article
- Human Cancer-Associated Mutations of SF3B1 Lead to a Splicing Modification of Its Own RNA.Cancers · 2020Article
- Ceramide Analogue SACLAC Modulates Sphingolipid Levels andMolecular cancer research : MCR · 2020Article
- Review
- Splicing, genome stability and disease: splice like your genome depends on it!Current genetics · 2019Review
- The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface.The Journal of biological chemistry · 2019Article
- Selective defects in gene expression control genome instability in yeast splicing mutants.Molecular biology of the cell · 2019Article
- Distinct transcriptomic and exomic abnormalities within myelodysplastic syndrome marrow cells.Leukemia & lymphoma · 2018Article
- PathwaySplice: an R package for unbiased pathway analysis of alternative splicing in RNA-Seq data.Bioinformatics (Oxford, England) · 2018Article
- Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics.Wiley interdisciplinary reviews. RNA · 2018Review
- Hereditary cancer genes are highly susceptible to splicing mutations.PLoS genetics · 2018Article
Corrections and comments
- Erratum for
Authors and funding
20 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.