ArticlePloS one2015
Identification of Candidate Coral Pathogens on White Band Disease-Infected Staghorn Coral.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 117 citations in OpenAlex.
- Opportunistic diseases in marine eukaryotes: Could Bacteroidota be the next threat to ocean life?Environmental microbiology · 2022Pooled it
- Microbiome Composition in a Common Mediterranean Bryozoan Following an Unprecedented Marine Heatwave.Environmental microbiology reports · 2025Article
- Interactive effects of ocean acidification and warming disrupt calcification and microbiome composition in bryozoans.Communications biology · 2025Article
- Antibiotic type and dose variably affect microbiomes of a disease-resistant Acropora cervicornis genotype.Environmental microbiome · 2025Article
- Article
- Halobacteriovorax halts disease progression in endangered Caribbean corals.The ISME journal · 2025Article
- Selective shaping of prokaryotic communities and core symbiont maintenance suggest large-scale aquarium facilities as reservoirs of microbiome diversity in octocorals.Frontiers in microbiology · 2025Article
- Genotypes of Acropora cervicornis in Florida show resistance to either elevated nutrients or disease, but not both in combination.PloS one · 2025Article
- Tank-based bacterial profiling identifies basin-wide white band disease pathogen candidate and no bacterial associations with coral disease resistance.ISME communications · 2025Article
- Coral high molecular weight carbohydrates support opportunistic microbes in bacterioplankton from an algae-dominated reef.mSystems · 2024Article
- Microscale sampling of the coral gastrovascular cavity reveals a gut-like microbial community.Animal microbiome · 2024Article
- Novel metagenomics analysis of stony coral tissue loss disease.G3 (Bethesda, Md.) · 2024Article
- Novel metagenomics analysis of stony coral tissue loss disease.bioRxiv : the preprint server for biology · 2024Article
- Article
- Article
- Bivalve microbiomes are shaped by host species, size, parasite infection, and environment.PeerJ · 2024Article
- DNA from non-viable bacteria biases diversity estimates in the corals Acropora loripes and Pocillopora acuta.Environmental microbiome · 2023Article
- Shifts in the coral microbiome in response toApplied and environmental microbiology · 2023Article
- The Impact of Highly Weathered Oil from the Most Extensive Oil Spill in Tropical Oceans (Brazil) on the Microbiome of the CoralMicroorganisms · 2023Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial diseases affecting scleractinian corals pose an enormous threat to the health of coral reefs, yet we still have a limited understanding of the bacteria associated with coral diseases. White band disease is a bacterial disease that affects the two Caribbean acroporid corals, the staghorn coral Acropora cervicornis and the elkhorn coral A. palmate. Species of Vibrio and Rickettsia have both been identified as putative WBD pathogens. Here we used Illumina 16S rRNA gene sequencing to profile the bacterial communities associated with healthy and diseased A. cervicornis collected from four field sites during two different years. We also exposed corals in tanks to diseased and healthy (control) homogenates to reduce some of the natural variation of field-collected coral bacterial communities. Using a combination of multivariate analyses, we identified community-level changes between diseased and healthy corals in both the field-collected and tank-exposed datasets. We then identified changes in the abundances of individual operational taxonomic units (OTUs) between diseased and healthy corals. By comparing the diseased and healthy-associated bacteria in field-collected and tank-exposed corals, we were able to identify 16 healthy-associated OTUs and 106 consistently disease-associated OTUs, which are good candidates for putative WBD pathogens. A large percentage of these disease-associated OTUs belonged to the order Flavobacteriales. In addition, two of the putative pathogens identified here belong to orders previously suggested as WBD pathogens: Vibronales and Rickettsiales.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.