ArticleNature communications2015
Unique metabolites protect earthworms against plant polyphenols.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 99 citations in OpenAlex.
- Fauna-microbe diversity coupling lost in agricultural soils: Implications from the bacteria hidden in earthworm gut.Fundamental research · 2025Article
- Soil Carbon Sequestration: Role of Fe Oxides and Polyphenol Oxidase Across Temperature and Cultivation Systems.Plants (Basel, Switzerland) · 2025Article
- Ecological and evolutionary responses of earthworm holobionts to environmental changes.The ISME journal · 2025Review
- Taxonomic and Functional Dynamics of Bacterial Communities During Drift Seaweed Vermicomposting.Microorganisms · 2024Article
- Ecological adaptation of earthworms for coping with plant polyphenols, heavy metals, and microplastics in the soil: A review.Heliyon · 2023Review
- Mass spectrometry-based metabolomics in microbiome investigations.Nature reviews. Microbiology · 2022Review
- In focus in HCB.Histochemistry and cell biology · 2022Article
- Classification of target tissues of Eisenia fetida using sequential multimodal chemical analysis and machine learning.Histochemistry and cell biology · 2022Article
- Soluble mediators of innate immunity in annelids and bivalve mollusks: A mini-review.Frontiers in immunology · 2022Review
- Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Direct Imaging of Plant Metabolites in the Rhizosphere Using Laser Desorption Ionization Ultra-High Resolution Mass Spectrometry.Frontiers in plant science · 2021Article
- High-quality genome assembly ofPeerJ · 2020Article
- Metabolite biomarkers of chlorothalonil exposure in earthworms, coelomic fluid, and coelomocytes.The Science of the total environment · 2019Article
- Drying Enhances Signal Intensities for Global GC⁻MS Metabolomics.Metabolites · 2019Article
- Article
- Combining bulk and amino acid stable isotope analyses to quantify trophic level and basal resources of detritivores: a case study on earthworms.Oecologia · 2019Article
- MSiReader v1.0: Evolving Open-Source Mass Spectrometry Imaging Software for Targeted and Untargeted Analyses.Journal of the American Society for Mass Spectrometry · 2018Article
- Article
- Tracing the fate and transport of secondary plant metabolites in a laboratory mesocosm experiment by employing mass spectrometric imaging.Analytical and bioanalytical chemistry · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All higher plants produce polyphenols, for defence against above-ground herbivory. These polyphenols also influence the soil micro- and macro-fauna that break down plant leaf litter. Polyphenols therefore indirectly affect the fluxes of soil nutrients and, ultimately, carbon turnover and ecosystem functioning in soils. It is unknown how earthworms, the major component of animal biomass in many soils, cope with high-polyphenol diets. Here, we show that earthworms possess a class of unique surface-active metabolites in their gut, which we term 'drilodefensins'. These compounds counteract the inhibitory effects of polyphenols on earthworm gut enzymes, and high-polyphenol diets increase drilodefensin concentrations in both laboratory and field populations. This shows that drilodefensins protect earthworms from the harmful effects of ingested polyphenols. We have identified the key mechanism for adaptation to a dietary challenge in an animal group that has a major role in organic matter recycling in soils worldwide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.