Evidence map›Paper›PMID 26241355›Full record

ArticleJournal of biomedical informatics2015

A systematic comparison of feature space effects on disease classifier performance for phenotype identification of five diseases.

Christopher Kotfila, Özlem Uzuner

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Ensembles of NLP Tools for Data Element Extraction from Clinical Notes.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2016
    Article
  8. Article
  9. Natural Language Processing for EHR-Based Computational Phenotyping.IEEE/ACM transactions on computational biology and bioinformatics
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christopher KotfilaInformatics Department, University at Albany, State University of New York, Albany, NY, USA. Electronic address: ckotfila@albany.edu.
Özlem UzunerDepartment of Information Studies, University at Albany, State University of New York, NY, USA.

Funding

Challenges in Natural Language Processing in Clinical TextR13LM011411 · NLM · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI UZUNER, OZLEM · 2012 to 2016
$98k
NLM NIH HHS R13 LM011411
6 · The paper itself

Abstract

Automated phenotype identification plays a critical role in cohort selection and bioinformatics data mining. Natural Language Processing (NLP)-informed classification techniques can robustly identify phenotypes in unstructured medical notes. In this paper, we systematically assess the effect of naive, lexically normalized, and semantic feature spaces on classifier performance for obesity, atherosclerotic cardiovascular disease (CAD), hyperlipidemia, hypertension, and diabetes. We train support vector machines (SVMs) using individual feature spaces as well as combinations of these feature spaces on two small training corpora (730 and 790 documents) and a combined (1520 documents) training corpus. We assess the importance of feature spaces and training data size on SVM model performance. We show that inclusion of semantically-informed features does not statistically improve performance for these models. The addition of training data has weak effects of mixed statistical significance across disease classes suggesting larger corpora are not necessary to achieve relatively high performance with these models.

Indexed as

Natural Language ProcessingCardiovascular DiseasesData MiningDecision Support Systems, ClinicalDiabetes MellitusDiagnosis, Computer-AssistedElectronic Health RecordsHumansNew YorkObesityPattern Recognition, AutomatedPhenotypeReproducibility of ResultsSensitivity and SpecificitySupport Vector MachineClassificationNatural language processingPhenotyping

Identifiers

PMID26241355
PMCPMC4994187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.