Centrosome biology: the ins and outs of centrosome assembly.

Suzanna L Prosser, Laurence Pelletier

Abstract readComment

In one paragraph

Article in Current biology : CB, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope.eLife · 2021
Article
A self-assembled cylindrical platform for Plk4-induced centriole biogenesis.Open biology · 2020
Review
Random chromosome distribution in the first meiosis of F1 disomic substitution line 2R(2D) x rye hybrids (ABDR, 4× = 28) occurs without bipolar spindle assembly.Comparative cytogenetics · 2020
Article
Tau-based fluorescent protein fusions to visualize microtubules.Cytoskeleton (Hoboken, N.J.) · 2017
Article
Centrosomal clustering contributes to chromosomal instability and cancer.Current opinion in biotechnology · 2016
Review
Oocyte Meiotic Spindle Assembly and Function.Current topics in developmental biology · 2016
Review
Flipping the switch: regulating MTOC location.Cell cycle (Georgetown, Tex.) · 2015
Article

4 · The record

Corrections and comments

Comment on
Isotropic incorporation of SPD-5 underlies centrosome assembly in C. elegans.2015
Comment on
Different Drosophila cell types exhibit differences in mitotic centrosome assembly dynamics.2015

5 · Who and what money

Authors and funding

2 authors.

Suzanna L ProsserLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada.

Laurence PelletierLunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, M5S 1A8, Canada. Electronic address: pelletier@lunenfeld.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a microtubule-organizing center, the centrosome undergoes a dramatic increase in size - via expansion of the pericentriolar material - during mitosis. Recent work reveals shared assembly properties of a protein scaffold that facilitates and supports this expansion, a process critical to spindle assembly.

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell Cycle ProteinsCentrosomeDrosophilaCaenorhabditis elegans ProteinsCell Cycle ProteinsSPD-5 protein, C elegans

Identifiers

PMID26241140

DOI10.1016/j.cub.2015.06.038

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.