Evidence map›Paper›PMID 26240615›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2015

Does elevated intra-abdominal pressure during laparoscopic colorectal surgery cause acute gastrointestinal injury?

Zhenghao Cai, Manu L N G Malbrain, Jing Sun, Ruijun Pan, Junjun Ma, Bo Feng, Feng Dong, Minhua Zheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Observational
  7. The effects of prolonged COWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zhenghao CaiRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Manu L N G MalbrainZiekenhuis Netwerk Antwerpen, ZNA Stuivenberg, Antwerpen, Belgium.
Jing SunRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ruijun PanRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Junjun MaRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Bo FengRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feng DongRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Minhua ZhengRuijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ruijin Hospital · CNShanghai Jiao Tong University · CNZiekenhuisnetwerk Antwerpen Stuivenberg · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe incidence of acute gastrointestinal injury (AGI) after colorectal surgery is low when laparoscopic techniques are used. While elevated intra-abdominal pressure (IAP) and intra-abdominal hypertension (IAH) are associated with AGI grade II, little is known about the relation between increased IAP during laparoscopy and subsequent AGI.

aimTo assess the impact of increased IAP during laparoscopic colorectal surgery on the incidence of postoperative AGI. MATERIAL AND

methodsSixty-six patients (41 men and 25 women) with colorectal cancer undergoing elective laparoscopic colorectal surgery were randomized into 3 groups, according to different IAP levels during CO2 pneumoperitoneum (10 mm Hg, 12 mm Hg and 15 mm Hg). We recorded the incidence of AGI after surgery by assessing the following parameters: time to first flatus/defecation, time to first bowel movement, time to tolerance of semi-liquid food and the occurrence of vomiting/diarrhea. Moreover, inflammatory mediators were measured before the induction of CO2 pneumoperitoneum and on postoperative day 1.

resultsAcute gastrointestinal injury occurred in 15 (27.3%) patients. In all 3 study groups, the elevation of IAP during CO2 pneumoperitoneum did not significantly increase the occurrence of symptoms of AGI, vomiting or diarrhea. Lower IAP levels did not significantly accelerate recovery of gastrointestinal function or shorten postoperative hospital stay. The changes in serum IL-6 after surgery did not correlate with the value of IAP.

conclusionsThe level of IAP elevation during laparoscopic colorectal surgery does not increase the occurrence of AGI after surgery.

Indexed as

acute gastrointestinal injurycolorectal carcinomainflammatory mediatorsintra-abdominal pressurelaparoscopic surgerypostoperative recovery

Identifiers

PMID26240615
PMCPMC4520847
OpenAlexW1079935208

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.