Evidence map›Paper›PMID 26240594›Full record

ReviewElectrolyte & blood pressure : E & BP2015

A Minireview on Vasopressin-regulated Aquaporin-2 in Kidney Collecting Duct Cells.

Eui-Jung Park, Tae-Hwan Kwon

Open access · hybridAbstract readReview
In one paragraph

Review in Electrolyte & blood pressure : E & BP, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Diurnal function and expression of aquaporins in the mouse kidney.American journal of physiology. Renal physiology · 2025
    Article
  3. Article
  4. Aquaporins in Urinary System.Advances in experimental medicine and biology · 2023
    Article
  5. Article
  6. The Genomes of Two Strains ofFrontiers in cellular and infection microbiology · 2022
    Article
  7. The Biology of Vasopressin.Biomedicines · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. AVP dynamically increases paracellular NaPflugers Archiv : European journal of physiology · 2017
    Review
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eui-Jung ParkDepartment of Biochemistry and Cell Biology, Kyungpook National University School of Medicine, Daegu, Korea.
Tae-Hwan KwonDepartment of Biochemistry and Cell Biology, Kyungpook National University School of Medicine, Daegu, Korea.
Kyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The kidney collecting duct is an important renal tubular segment for the regulation of body water and salt homeostasis. Water reabsorption in the collecting duct cells is regulated by arginine vasopressin (AVP) via the vasopressin V2-receptor (V2R). AVP increases the osmotic water permeability of the collecting duct cells through aquaporin-2 (AQP2) and aquaporin-3 (AQP3). AVP induces the apical targeting of AQP2 and transcription of AQP2 gene in the kidney collecting duct principal cells. The signaling transduction pathways resulting in the AQP2 trafficking to the apical plasma membrane of the collecting duct principal cells, include AQP2 phosphorylation, RhoA phosphorylation, actin depolymerization and calcium mobilization, and the changes of AQP2 protein abundance in water balance disorders have been extensively studied. These studies elucidate the underlying cellular and molecular mechanisms of body water homeostasis and provide the basis for the treatment of body water balance disorders.

Indexed as

AquaporinsArginine vasopressinBody water balance

Identifiers

PMID26240594
PMCPMC4520882
OpenAlexW938832151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.