Evidence map›Paper›PMID 26240438›Full record

ArticleInternational journal of engineering science2015

Study of blood flow in several benchmark micro-channels using a two-fluid approach.

Wei-Tao Wu, Fang Yang, James F Antaki, Nadine Aubry, Mehrdad Massoudi

Abstract read
In one paragraph

Article in International journal of engineering science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Simulation of blood flow in a sudden expansion channel and a coronary artery.Journal of computational and applied mathematics · 2020
    Article
  4. Article
  5. A non-linear fluid suspension model for blood flow.International journal of non-linear mechanics · 2019
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei-Tao WuDepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Fang YangDepartment of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
James F AntakiDepartment of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.
Nadine AubryDepartment of Mechanical Engineering, Northeastern University, Boston, MA, 02115, USA.
Mehrdad MassoudiU. S. Department of Energy, National Energy Technology Laboratory (NETL), PA, 15236, USA.

Funding

Multiscale Model of Thrombosis in Artificial CirculationR01HL089456 · NHLBI · CORNELL UNIVERSITY · PI ANTAKI, JAMES F., BUTCHER, JONATHAN TALBOT · 2009 to 2024
$8.5M
NHLBI NIH HHS R01 HL089456
6 · The paper itself

Abstract

It is known that in a vessel whose characteristic dimension (e.g., its diameter) is in the range of 20 to 500 microns, blood behaves as a non-Newtonian fluid, exhibiting complex phenomena, such as shear-thinning, stress relaxation, and also multi-component behaviors, such as the Fahraeus effect, plasma-skimming, etc. For describing these non-Newtonian and multi-component characteristics of blood, using the framework of mixture theory, a two-fluid model is applied, where the plasma is treated as a Newtonian fluid and the red blood cells (RBCs) are treated as shear-thinning fluid. A computational fluid dynamic (CFD) simulation incorporating the constitutive model was implemented using OpenFOAM® in which benchmark problems including a sudden expansion and various driven slots and crevices were studied numerically. The numerical results exhibited good agreement with the experimental observations with respect to both the velocity field and the volume fraction distribution of RBCs.

Indexed as

Bloodcrevicesmicro-channelsmixture theoryshear-thinningtwo-component flow

Identifiers

PMID26240438
PMCPMC4521229

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.