ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2015
Pulse trains to percepts: the challenge of creating a perceptually intelligible world with sight recovery technologies.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of extended reality (XR) for understanding and augmenting vision loss.Journal of vision · 2023Pooled it
- A virtual patient simulation modeling the neural and perceptual effects of human visual cortical stimulation, from pulse trains to percepts.Scientific reports · 2024Article
- Human-in-the-Loop Optimization for Deep Stimulus Encoding in Visual Prostheses.Advances in neural information processing systems · 2023Article
- Towards aJournal of neural engineering · 2022Article
- Immersive Virtual Reality Simulations of Bionic Vision.Augmented Humans 2022 · 2022Article
- Factors affecting two-point discrimination in Argus II patients.Frontiers in neuroscience · 2022Article
- Learning to see again: Perceptual learning of simulated abnormal on- off-cell population responses in sighted individuals.Journal of vision · 2021Article
- A Computational Model of Phosphene Appearance for Epiretinal Prostheses.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021Article
- Perceptual Learning of Object Recognition in Simulated Retinal Implant Perception - The Effect of Video Training.Translational vision science & technology · 2021Article
- The impact of synchronous versus asynchronous electrical stimulation in artificial vision.Journal of neural engineering · 2021Review
- Oculomotor Responses to Dynamic Stimuli in a 44-Channel Suprachoroidal Retinal Prosthesis.Translational vision science & technology · 2020Article
- Harmonization of Outcomes and Vision Endpoints in Vision Restoration Trials: Recommendations from the International HOVER Taskforce.Translational vision science & technology · 2020Article
- An update on retinal prostheses.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2020Review
- Probing and predicting ganglion cell responses to smooth electrical stimulation in healthy and blind mouse retina.Scientific reports · 2020Article
- Model-Based Recommendations for Optimal Surgical Placement of Epiretinal Implants.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2019Article
- A model of ganglion axon pathways accounts for percepts elicited by retinal implants.Scientific reports · 2019Article
- Spatiotemporal Pixelization to Increase the Recognition Score of Characters for Retinal Prostheses.Sensors (Basel, Switzerland) · 2017Article
- Learning to see again: biological constraints on cortical plasticity and the implications for sight restoration technologies.Journal of neural engineering · 2017Review
- Visual Prosthesis: Interfacing Stimulating Electrodes with Retinal Neurons to Restore Vision.Frontiers in neuroscience · 2017Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
An extraordinary variety of sight recovery therapies are either about to begin clinical trials, have begun clinical trials, or are currently being implanted in patients. However, as yet we have little insight into the perceptual experience likely to be produced by these implants. This review focuses on methodologies, such as optogenetics, small molecule photoswitches and electrical prostheses, which use artificial stimulation of the retina to elicit percepts. For each of these technologies, the interplay between the stimulating technology and the underlying neurophysiology is likely to result in distortions of the perceptual experience. Here, we describe some of these potential distortions and discuss how they might be minimized either through changes in the encoding model or through cortical plasticity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.