Evidence map›Paper›PMID 26240329›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

Critical waves and the length problem of biology.

Robert B Laughlin

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Mitotic Cdc42 waves encode PI(3,4)PScience advances · 2026
    Article
  2. The Min-protein oscillations inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Review
  3. Rhythmicity and waves in the cortex of single cells.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Review
  4. Chemical waves in cell and developmental biology.The Journal of cell biology · 2018
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Robert B LaughlinDepartment of Physics, Stanford University, Stanford, CA 94305 rbl@large.stanford.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is pointed out that the mystery of how biological systems measure their lengths vanishes away if one premises that they have discovered a way to generate linear waves analogous to compressional sound. These can be used to detect length at either large or small scales using echo timing and fringe counting. It is shown that suitable linear chemical potential waves can, in fact, be manufactured by tuning to criticality conventional reaction-diffusion with a small number substance. Min oscillations in Escherichia coli are cited as precedent resonant length measurement using chemical potential waves analogous to laser detection. Mitotic structures in eukaryotes are identified as candidates for such an effect at higher frequency. The engineering principle is shown to be very general and functionally the same as that used by hearing organs.

Indexed as

Adenosine TriphosphatasesAnimalsBacterial ProteinsBiomedical EngineeringBiophysical PhenomenaCell Cycle ProteinsCytoskeletal ProteinsDiffusionEscherichia coliEscherichia coli ProteinsGiant CellsLasersModels, BiologicalMotionNeuronsOscillometryAdenosine TriphosphatasesBacterial ProteinsCell Cycle ProteinsCytoskeletal ProteinsEscherichia coli ProteinsFtsZ protein, BacteriaMinD protein, E coliMinE protein, E coligrowth and formlaser amplifierMinDEmitosiswaves

Identifiers

PMID26240329
PMCPMC4547306

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.