Evidence map›Paper›PMID 26240262›Full record

ArticleCirculation2015

Distinctive Clinical Profile of Blacks Versus Whites Presenting With Sudden Cardiac Arrest.

Kyndaron Reinier, Gregory A Nichols, Adriana Huertas-Vazquez, Audrey Uy-Evanado, Carmen Teodorescu, Eric C Stecker, Karen Gunson, Jonathan Jui, Sumeet S Chugh

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  9. Epidemiology of out-of-hospital cardiac arrest: comparison of Turkish nationals and refugees.Malawi medical journal : the journal of Medical Association of Malawi · 2023
    Article
  10. Survival After Out-of-Hospital Cardiac Arrest: The Role of Racial Residential Segregation.Journal of urban health : bulletin of the New York Academy of Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kyndaron ReinierFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Gregory A NicholsFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Adriana Huertas-VazquezFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Audrey Uy-EvanadoFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Carmen TeodorescuFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Eric C SteckerFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Karen GunsonFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Jonathan JuiFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland.
Sumeet S ChughFrom The Heart Institute, Cedars-Sinai Medical Center, Los Angeles CA (K.R., A.H.-V., A.U.-E., C.T., S.S.C.); Kaiser Permanente Center for Health Research, Portland, OR (G.A.N.); and Knight Cardiovascular Institute (E.C.S.), Department of Pathology (K.G.), and Department of Emergency Medicine (J.J.), Oregon Health and Science University, Portland. sumeet.chugh@cshs.org.
Kaiser Permanente Center for Health Research · US

Funding

Oregon Multidisciplinary Training Program in Emergency Medicine Clinical ResearchK12HL108974 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI NEWGARD, CRAIG D. · 2011 to 2015
$3.8M
Sudden Cardiac Death in Middle AgeR01HL122492 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHUGH, SUMEET S. · 2015 to 2018
$2.2M
Prolonged Ventricular Depolarization and Sudden Death in the CommunityR01HL105170 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI CHUGH, SUMEET S. · 2010 to 2013
$1.6M
NHLBI NIH HHS K12 HL108974NHLBI NIH HHS R01 HL105170NHLBI NIH HHS R01HL105170NHLBI NIH HHS R01 HL122492NHLBI NIH HHS R01HL122492
6 · The paper itself

Abstract

backgroundSudden cardiac arrest (SCA) is a major contributor to mortality, but data are limited among nonwhites. Identification of differences in clinical profile based on race may provide opportunities for improved SCA prevention. METHODS AND

resultsIn the ongoing Oregon Sudden Unexpected Death Study (SUDS), individuals experiencing SCA in the Portland, OR, metropolitan area were identified prospectively. Patient demographics, arrest circumstances, and pre-SCA clinical profile were compared by race among cases from 2002 to 2012 (for clinical history, n=126 blacks, n=1262 whites). Incidence rates were calculated for cases from the burden assessment phase (2002-2005; n=1077). Age-adjusted rates were 2-fold higher among black men and women (175 and 90 per 100 000, respectively) compared with white men and women (84 and 40 per 100 000, respectively). Compared with whites, blacks were >6 years younger at the time of SCA and had a higher prearrest prevalence of diabetes mellitus (52% versus 33%; P<0.0001), hypertension (77% versus 65%; P=0.006), and chronic renal insufficiency (34% versus 19%; P<0.0001). There were no racial differences in previously documented coronary artery disease or left ventricular dysfunction, but blacks had more prevalent congestive heart failure (43% versus 34%; P=0.04) and left ventricular hypertrophy (77% versus 58%; P=0.02) and a longer QTc interval (466±36 versus 453±41 milliseconds; P=0.03).

conclusionsIn this US community, the burden of SCA was significantly higher in blacks compared with whites. Blacks with SCA had a higher prearrest prevalence of risk factors beyond established coronary artery disease, providing potential targets for race-specific prevention.

Indexed as

AgedAged, 80 and overBlack or African AmericanBlack PeopleDeath, Sudden, CardiacDiabetes ComplicationsFemaleHumansHypertensionIncidenceMaleMiddle AgedOregonPrevalenceProspective StudiesRenal Insufficiency, Chronicdeathdiabetes mellitushypertensionhypertrophyleft ventricularrisk factorssudden

Identifiers

PMID26240262
PMCPMC4526124
OpenAlexW2157560272

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.