Evidence map›Paper›PMID 26240175›Full record

ReviewJournal of cell science2015

The Exocyst at a Glance.

Bin Wu, Wei Guo

Abstract readReview
In one paragraph

Review in Journal of cell science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 156 papers.

0numbers the graph read from it
0cells of the map it votes in
156citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

156 citing papers in PubMed.

  1. Article
  2. Review
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  4. Review
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  14. Preassembly and independent trafficking of the exocyst complex inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
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  18. Article
  19. Article
  20. Article

96 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bin WuDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Wei GuoDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA guowei@sas.upenn.edu.

Funding

The Role of the Exocyst in Cell MigrationR01GM085146 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GUO, WEI · 2009 to 2020
$4.1M
Molecular Regulation of ExocytosisR01GM111128 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GUO, WEI · 2014 to 2020
$2.4M
NIGMS NIH HHS GM085146NIGMS NIH HHS GM111128NIGMS NIH HHS R01 GM085146NIGMS NIH HHS R01 GM111128
6 · The paper itself

Abstract

The exocyst is an octameric protein complex that is implicated in the tethering of secretory vesicles to the plasma membrane prior to SNARE-mediated fusion. Spatial and temporal control of exocytosis through the exocyst has a crucial role in a number of physiological processes, such as morphogenesis, cell cycle progression, primary ciliogenesis, cell migration and tumor invasion. In this Cell Science at a Glance poster article, we summarize recent works on the molecular organization, function and regulation of the exocyst complex, as they provide rationales to the involvement of this complex in such a diverse array of cellular processes.

Indexed as

AnimalsCell CycleCell MembraneExocytosisHumansMembrane FusionMembrane Fusion ProteinsMorphogenesisrab GTP-Binding Proteinsral Guanine Nucleotide Exchange FactorVesicular Transport ProteinsEXOC7 protein, humanMembrane Fusion Proteinsrab GTP-Binding Proteinsral Guanine Nucleotide Exchange FactorVesicular Transport ProteinsExocystMembrane fusionRabRalRhoVesicle tether

Identifiers

PMID26240175
PMCPMC4541039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.