ArticleScientific reports2015
Real-Time MRI-Guided Catheter Tracking Using Hyperpolarized Silicon Particles.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Recent Developments in Porous Silicon Nanovectors with Various Imaging Modalities in the Framework of Theranostics.ChemMedChem · 2022Review
- Heat-Mitigated Design and Lorentz Force-Based Steering of an MRI-Driven Microcatheter toward Minimally Invasive Surgery.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Post-Acquisition HyperpolarizedDiagnostics (Basel, Switzerland) · 2022Article
- Electroplated waveguides to enhance DNP and EPR spectra of silicon and diamond particles.Magnetic resonance (Gottingen, Germany) · 2022Article
- Hyperpolarized MRI with silicon micro and nanoparticles: Principles and applications.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021Review
- Dynamic Nuclear Polarization of Silicon Carbide Micro- and Nanoparticles.ACS applied materials & interfaces · 2021Article
- Real-time 3T MRI-guided cardiovascular catheterization in a porcine model using a glass-fiber epoxy-based guidewire.PloS one · 2020Article
- Nanometer size silicon particles for hyperpolarized MRI.Scientific reports · 2017Article
- Developing hyperpolarized silicon particles for in vivo MRI targeting of ovarian cancer.Journal of medical imaging (Bellingham, Wash.) · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Visualizing the movement of angiocatheters during endovascular interventions is typically accomplished using x-ray fluoroscopy. There are many potential advantages to developing magnetic resonance imaging-based approaches that will allow three-dimensional imaging of the tissue/vasculature interface while monitoring other physiologically-relevant criteria, without exposing the patient or clinician team to ionizing radiation. Here we introduce a proof-of-concept development of a magnetic resonance imaging-guided catheter tracking method that utilizes hyperpolarized silicon particles. The increased signal of the silicon particles is generated via low-temperature, solid-state dynamic nuclear polarization, and the particles retain their enhanced signal for ≥ 40 minutes--allowing imaging experiments over extended time durations. The particles are affixed to the tip of standard medical-grade catheters and are used to track passage under set distal and temporal points in phantoms and live mouse models. With continued development, this method has the potential to supplement x-ray fluoroscopy and other MRI-guided catheter tracking methods as a zero-background, positive contrast agent that does not require ionizing radiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.