Evidence map›Paper›PMID 26239514›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2015

Negative-Pressure Wound Therapy in the Management of High-Grade Ventral Hernia Repairs.

Nelson Rodriguez-Unda, Kevin C Soares, Saïd C Azoury, Pablo A Baltodano, Caitlin W Hicks, Karen K Burce, Peter Cornell, Carisa M Cooney, Frederic E Eckhauser

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04455724 (Negative Pressure Incisional Wound Therapy for High-risk Ventral Hernia Repair), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04455724 nacompletednot on this mapstarted 2020, after this paper: background citation

Negative Pressure Incisional Wound Therapy for High-risk Ventral Hernia Repair: a Randomized Controlled Trial

TypeinterventionalSponsorMcMaster UniversityRan2020 to 2024Enrolled110ConditionsVentral HerniaArmsNegative pressure incisional wound therapy, Standard sterile dressing
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Component separation and large incisional hernia: predictive factors of recurrence.Hernia : the journal of hernias and abdominal wall surgery · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Observational
  11. A novel, validated risk score to predict surgical site infection after pancreaticoduodenectomy.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nelson Rodriguez-UndaDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Kevin C SoaresDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Saïd C AzouryDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Pablo A BaltodanoDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Caitlin W HicksDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Karen K BurceDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Peter CornellDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Carisa M CooneyDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA.
Frederic E EckhauserDepartment of Surgery, Johns Hopkins University School of Medicine, Blalock 618, 600 N. Wolfe Street, Baltimore, MD, 21287, USA. feckhau2@jhmi.edu.
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite improved operative techniques, open ventral hernia repair (VHR) surgery in high-risk, potentially contaminated patients remains challenging. As previously reported by our group, the use of a modified negative-pressure wound therapy system (hybrid-VAC or HVAC) in patients with grade 2 hernias is associated with lower surgical site occurrence (SSO) and surgical site infection (SSI) rates. Accordingly, the authors aim to evaluate whether the HVAC would similarly improve surgical site outcomes following VHR in patients with grade 3 hernias.

methodsA 4-year retrospective review (2011-2014) was conducted of all consecutive, modified ventral hernia working group (VHWG) grade 3 hernia repairs with HVAC closure performed by a single surgeon (FEE) at a single institution. Operative data and 90-day outcomes were evaluated. Overall outcomes (e.g., recurrence, reoperation, mortality) were reviewed for the study group.

resultsA total of 117 patients with an average age of 56.7 ± 11.9 years were classified as grade 3 hernias and underwent open VHR with subsequent HVAC closure. Fifty patients were male (42.7 %), the mean BMI was 35.2 (±9.5), and 60.7 % had a history of prior hernia repair. The average fascial defect size was 201.5 (±167.3) cm(2) and the mean length of stay was 14.2 (±9.3) days. Ninety-day outcomes showed an SSO rate of 20.7 % and an SSI rate of 5.2 %. The overall hernia recurrence rate was 4.2 % (n=6) with a mean follow-up of 11 ± 7.3 months.

conclusionModified VHWG grade 3 ventral hernias are associated with significant morbidity. In our series utilizing the HVAC system after VHR, the observed rate of SSO and SSI compared favorably to reported series. Further prospective cost-effective studies are warranted to validate these findings.

Indexed as

Negative-Pressure Wound TherapyAdultAgedFemaleHernia, VentralHerniorrhaphyHumansMaleMiddle AgedRecurrenceReoperationRetrospective StudiesSurgical Wound Infectionabdominal wall reconstructionGrade 3 herniaNegative pressure wound therapySurgical site infectionVacuum-assisted closureVentral hernia

Identifiers

PMID26239514
OpenAlexW1069054720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.