Evidence map›Paper›PMID 26239488›Full record

ArticleJournal of child neurology2016

Skin Ulcers and Mortality Among Adolescents and Young Adults With Spina Bifida in South Carolina During 2000-2010.

Bo Cai, Suzanne McDermott, Yinding Wang, Julie A Royer, Joshua R Mann, James W Hardin, Orgul Ozturk, Lijing Ouyang

Open access · greenAbstract read
In one paragraph

Article in Journal of child neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bo CaiDepartment of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, SC, USA BOCAI@mailbox.sc.edu.
Suzanne McDermottDepartment of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, SC, USA.
Yinding WangDepartment of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, SC, USA.
Julie A RoyerDivision of Research and Statistics, South Carolina Revenue and Fiscal Affairs, Columbia, SC, USA.
Joshua R MannDepartment of Family and Preventive Medicine, University of South Carolina School of Medicine, Columbia, SC, USA.
James W HardinDepartment of Epidemiology and Biostatistics, University of South Carolina Arnold School of Public Health, Columbia, SC, USA.
Orgul OzturkDepartment of Economics, University of South Carolina, Moore School of Business, Columbia, SC, USA.
Lijing OuyangCenters for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities, Atlanta, GA, USA.
University of South Carolina · USNational Center on Birth Defects and Developmental Disabilities · US

Funding

South Carolina Study for Adolescents and Young Adults with Rare ConditionsU01DD000776 · DD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI MCDERMOTT, SUZANNE W · 2011 to 2013
$1.2M
Intramural CDC HHS CC999999NCBDD CDC HHS 5U01DD000776-03NCBDD CDC HHS U01 DD000776
6 · The paper itself

Abstract

The authors investigated 48 deaths (7% death rate) among 690 adolescents and young adults with spina bifida in South Carolina during 2000-2010. The authors used Medicaid and other administrative data and a retrospective cohort design that included people with spina bifida identified using ICD-9 codes. Cox regression models with time-dependent and time-invariant covariates, and Kaplan-Meier survival curves were constructed. The authors found that 21.4% of the study group had a skin ulcer during the study period and individuals with skin ulcers had significantly higher mortality than those without ulcers (P < .0001). People who had their first skin ulcer during adolescence had higher mortality than those who had the first skin ulcer during young adulthood (P = .0002; hazard ratio = 10.70, 95% confidence interval for hazard ratio: 3.01, 38.00) and those without skin ulcers, controlling for other covariates. This study showed that age at which individuals first had a skin ulcer was associated with mortality.

Indexed as

AdolescentFemaleHumansKaplan-Meier EstimateMaleProportional Hazards ModelsRetrospective StudiesSkin UlcerSouth CarolinaSpinal DysraphismYoung AdultAdolescenthealthskin ulcerspina bifidasurvival analysisyoung adult

Identifiers

PMID26239488
PMCPMC4740267
OpenAlexW1867221214

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.