ReviewJournal of clinical medicine2015
Advancements in Pharmacotherapy for Noncancerous Manifestations of HPV.
Review in Journal of clinical medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03625960 (Trichloroacetic Acid Versus Cantharone for the Treatment of Perenial Warts), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Trichloroacetic Acid Versus Cantharone for the Treatment of Perenial Warts
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical guideline for the diagnosis and treatment of cutaneous warts (2022).Journal of evidence-based medicine · 2022Guideline
- Characterization of type-specific HPV prevalence in a population of persistent cutaneous warts in Flanders, Belgium.Scientific reports · 2023Trial
- The efficacy of intralesional vitamin D3 injection in the treatment of cutaneous warts: A clinical therapeutic trial study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023Trial
- Cantharidin is Superior to Trichloroacetic Acid for the Treatment of Non-mucosal Genital Warts: A Pilot Randomized Controlled Trial.Clinical and experimental obstetrics & gynecology · 2018Trial
- HPV16 E2 protein possesses intrinsic helicase activity and sterically hinders E1 function through direct interaction.The Journal of biological chemistry · 2026Article
- Randomized Phase IIa Trial of Purified Candida Antigen for Common Warts: Evaluating the Safety and Efficacy Across Multiple Dosing Regimens.Dermatology and therapy · 2025Article
- Evaluation of Knowledge of Human Papillomavirus Infection and Its Oral Health Implications: A Comparative Study of Polish Medical and Dental Students.Journal of clinical medicine · 2025Article
- HPV Infection in Children and Adolescents-A Comprehensive Review.Journal of clinical medicine · 2025Review
- HPV Infections-Classification, Pathogenesis, and Potential New Therapies.International journal of molecular sciences · 2024Review
- Therapeutic Role of HPV Vaccination on Benign HPV-induced Epithelial Proliferations in Immunocompetent and Immunocompromised Patients: Case Study and Review of the Literature.Open forum infectious diseases · 2024Review
- A global study on knowledge and perception of HPV and HPV vaccination among young obstetricians and gynecologists.Turkish journal of obstetrics and gynecology · 2024Article
- Low-dose oral isotretinoin in the treatment of recalcitrant facial flat warts: A clinical case and review of literature.Health science reports · 2023Article
- Review
- Successful Treatment of Multiple Plantar and Periungual Warts by Local Hyperthermia Treatment: A Case Report.Clinical, cosmetic and investigational dermatology · 2023Article
- Tradition to Pathogenesis: A Novel Hypothesis for Elucidating the Pathogenesis of Diseases Based on the Traditional Use of Medicinal Plants.Frontiers in pharmacology · 2021Review
- Applications of a Standardized Green Tea Catechin Preparation for Viral Warts and Human Papilloma Virus-Related and Unrelated Cancers.Molecules (Basel, Switzerland) · 2020Review
- Case of giant vulvar condyloma acuminata successfully treated with imiquimod 3.75% cream: A case report.SAGE open medical case reports · 2018Article
- Successful treatment of plantar warts with intralesional bleomycin and electroporation: pilot prospective study.Dermatology practical & conceptual · 2017Article
- Formaldehyde 5% in Flexible Collodion Compared to Cryotherapy for Treatment of Female Genital Warts: A Randomized Clinical Trial.Indian journal of dermatologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human papillomavirus (HPV) is the most common sexually transmitted disease. Via infection of the basal epithelial cells, HPV causes numerous malignancies and noncancerous cutaneous manifestations. Noncancerous cutaneous manifestations of HPV, including common, plantar, plane, and anogenital warts, are among the most common reasons for an office visit. Although there are various therapies available, they are notoriously difficult to treat. HPV treatments can be grouped into destructive (cantharidin, salicylic acid), virucidal (cidofovir, interferon-α), antimitotic (bleomycin, podophyllotoxin, 5-fluorouracil), immunotherapy (Candida antigen, contact allergen immunotherapy, imiquimod) or miscellaneous (trichloroacetic acid, polyphenon E). The mechanism of action, recent efficacy data, safety profile and recommended regimen for each of these treatment modalities is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.