ArticleArchives of virology2015
Antiviral effect of lithium chloride on feline calicivirus in vitro.
Article in Archives of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Isolation and molecular characteristics of a recombinant feline calicivirus from Qingdao, China.Veterinary research forum : an international quarterly journal · 2023Article
- An overview of solutions for airborne viral transmission reduction related to HVAC systems including liquid desiccant air-scrubbing.Energy (Oxford, England) · 2022Article
- Lithium chloride inhibits infectious bronchitis virus-induced apoptosis and inflammation.Microbial pathogenesis · 2022Article
- Antiviral Effect of Lithium Chloride on Replication of Marek's Disease Virus in Chicken Embryonic Fibroblasts.International journal of molecular sciences · 2021Article
- Feline calicivirus strain 2280 p30 antagonizes type I interferon-mediated antiviral innate immunity through directly degrading IFNAR1 mRNA.PLoS pathogens · 2020Article
- Antiviral effect of copper chloride on feline calicivirus and synergy with ribavirin in vitro.BMC veterinary research · 2020Article
- Lithium's antiviral effects: a potential drug for CoViD-19 disease?International journal of bipolar disorders · 2020Review
- Does Lithium Deserve a Place in the Treatment Against COVID-19? A Preliminary Observational Study in Six Patients, Case Report.Frontiers in pharmacology · 2020Article
- Equine immunoglobulin F(ab')International immunopharmacology · 2019Article
- Antiviral effect of lithium chloride on porcine epidemic diarrhea virus in vitro.Research in veterinary science · 2018Article
- Identification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline viruses.International journal of biological macromolecules · 2017Article
- In vitro antiviral effect of germacrone on feline calicivirus.Archives of virology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feline calicivirus (FCV) is a highly contagious pathogen that causes oral and upper respiratory tract disease in cats. Despite widespread vaccination, the prevalence of FCV remains high. Furthermore, a high gene mutation rate has led to the emergence of variants, and some infections are lethal. To date, there is no effective antiviral drug available for treating FCV infection. Here, we show that lithium chloride (LiCl) effectively suppresses the replication of FCV strain F9 in Crandell-Reese feline kidney (CRFK) cells. The antiviral activity of LiCl occurred primarily during the early stage of infection and in a dose-dependent manner. LiCl treatment also inhibited the cytopathic effect. LiCl treatment exhibited a strong inhibitory effect against a panel of other two reference strains and two recent FCV isolates from China. These results demonstrate that LiCl might be an effective anti-FCV drug for controlling FCV disease. Further studies are required to explore the antiviral activity of LiCl against FCV replication in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.