ArticleMarine biotechnology (New York, N.Y.)2015
Low-Toxicity Diindol-3-ylmethanes as Potent Antifouling Compounds.
Article in Marine biotechnology (New York, N.Y.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 50 citations in OpenAlex.
- Genomic potential of crustose coralline algae-associated bacteria for the biosynthesis of novel antimicrobials.Microbial genomics · 2025Article
- Research Progress on New Environmentally Friendly Antifouling Coatings in Marine Settings: A Review.Biomimetics (Basel, Switzerland) · 2023Review
- Anti-Virulence Activity of 3,3'-Diindolylmethane (DIM): A Bioactive Cruciferous Phytochemical with Accelerated Wound Healing Benefits.Pharmaceutics · 2022Article
- Anti-Larval and Anti-Algal Natural Products from Marine Microorganisms as Sources of Anti-Biofilm Agents.Marine drugs · 2022Review
- Discovery, Yield Improvement, and Application in Marine Coatings of Potent Antifouling Compounds Albofungins Targeting Multiple Fouling Organisms.Frontiers in microbiology · 2022Article
- A Family of Nonribosomal Peptides Modulate Collective Behavior in Pseudovibrio Bacteria Isolated from Marine Sponges*.Angewandte Chemie (International ed. in English) · 2021Article
- Marine Natural Products from Tunicates and Their Associated Microbes.Marine drugs · 2021Review
- Bacterial Tropone Natural Products and Derivatives: Overview of their Biosynthesis, Bioactivities, Ecological Role and Biotechnological Potential.Chembiochem : a European journal of chemical biology · 2020Review
- The Plant Alkaloid Camptothecin as a Novel Antifouling Compound for Marine Paints: Laboratory Bioassays and Field Trials.Marine biotechnology (New York, N.Y.) · 2018Article
- Ecology and Biotechnological Potential of Bacteria Belonging to the Genus Pseudovibrio.Applied and environmental microbiology · 2018Review
- Mini-Review: Antifouling Natural Products from Marine Microorganisms and Their Synthetic Analogs.Marine drugs · 2017Review
- Review
- Thielavins W-Z₇, New Antifouling Thielavins from the Marine-Derived Fungus Thielavia sp. UST030930-004.Marine drugs · 2017Article
- Antifouling phenyl ethers and other compounds from the invertebrates and their symbiotic fungi collected from the South China Sea.AMB Express · 2016Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, eight natural products that belonged to di(1H-indol-3-yl)methane (DIM) family were isolated from Pseudovibrio denitrificans UST4-50 and tested for their antifouling activity against larval settlement (including both attachment and metamorphosis) of the barnacle Balanus (=Amphibalanus) amphitrite and the bryozoan Bugula neritina. All diindol-3-ylmethanes (DIMs) showed moderate to strong inhibitory effects against larval settlement of B. amphitrite with EC50 values ranging from 18.57 to 1.86 μM and could be considered as low-toxicity antifouling compounds since their LC50/EC50 ratios were larger than 15. Furthermore, the DIM- and 4-(di(1H-indol-3-yl)methyl)phenol (DIM-Ph-4-OH)-treated larvae completed normal settlement when they were transferred to clean seawater after being exposed to those compounds for 24 h. DIM also showed comparable antifouling performance to the commercial antifouling biocide Sea-Nine 211(™) in the field test over a period of 5 months, which further confirmed that DIMs can be considered as promising candidates of environmentally friendly antifouling compounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.