ReviewCurrent cardiology reports2015
Work Stress as a Risk Factor for Cardiovascular Disease.
Review in Current cardiology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 208 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Mindfulness-based Cognitive Behavior Therapy on Occupational Stress Management Among Community Secondary School Teachers in Kathmandu
Assessing the Effectiveness of a Holistic Semi-tailormade Well-being Intervention at Work: Study Protocol of a Partially Randomized Preference Trial Design
Who cites it
208 citing papers in PubMed, 11 syntheses or guidelines pooled it, 497 citations in OpenAlex.
- Enhancing wellness: a systematic review of biofeedback interventions for healthcare professionals.Frontiers in psychiatry · 2026Pooled it
- Psychosocial stress and stroke risk: meta-analysis of observational studies.Frontiers in neurology · 2025Pooled it
- The influence of burnout on cardiovascular disease: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Work Exposures and Development of Cardiovascular Diseases: A Systematic Review.Annals of work exposures and health · 2022Pooled it
- A systematic review of racial/ethnic and socioeconomic disparities in COVID-19.International journal for equity in health · 2021Pooled it
- Associations of working conditions and chronic low-grade inflammation among employees: a systematic review and meta-analysis.Scandinavian journal of work, environment & health · 2021Pooled it
- Psychosocial work exposures and health outcomes: a meta-review of 72 literature reviews with meta-analysis.Scandinavian journal of work, environment & health · 2021Pooled it
- Physical relaxation for occupational stress in healthcare workers: A systematic review and network meta-analysis of randomized controlled trials.Journal of occupational health · 2021Pooled it
- Long Working Hours and Risk of Cardiovascular Disease.Current cardiology reports · 2018Pooled it
- Work-related stress as a cardiovascular risk factor in police officers: a systematic review of evidence.International archives of occupational and environmental health · 2018Pooled it
- A systematic review of studies in the contributions of the work environment to ischaemic heart disease development.European journal of public health · 2016Pooled it
- Effects of taVNS on physiological responses and cognitive performance during a mental stressor.Cognitive, affective & behavioral neuroscience · 2025Trial
- Working Women Walking Program: A Sequential Multiple Assignment Randomized Trial.Journal of physical activity & health · 2025Trial
- Employee Cardiometabolic Risk Following a Cluster-Randomized Workplace Intervention From the Work, Family and Health Network, 2009-2013.American journal of public health · 2023Trial
- Yoga complemented cognitive behavioral therapy on job burnout among teachers of children with autism spectrum disorders.Medicine · 2021Trial
- Exploring the Effects of a Brief Biofeedback Breathing Session Delivered Through the BioBase App in Facilitating Employee Stress Recovery: Randomized Experimental Study.JMIR mHealth and uHealth · 2020Trial
- Mental and physical health effects of meaningful work and rewarding family responsibilities.PloS one · 2019Trial
- Essential Oil of Japanese Cedar (Cryptomeria japonica) Wood Increases Salivary Dehydroepiandrosterone Sulfate Levels after Monotonous Work.International journal of environmental research and public health · 2017Trial
- Multi-omics characterization of chronic social defeat stress recall-activated nuclei in Arc-GFP mice.Molecular psychiatry · 2026Article
- Chronic Occupational Stress and Immune-Inflammatory Dysregulation: Mechanisms, Clinical Consequences, Biomarkers and Implications for Occupational Medicine.Diagnostics (Basel, Switzerland) · 2026Review
148 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The role of psychosocial work stress as a risk factor for chronic disease has been the subject of considerable debate. Many researchers argue in support of a causal connection while others remain skeptical and have argued that the effect on specific health conditions is either negligible or confounded. This review of evidence from over 600,000 men and women from 27 cohort studies in Europe, the USA and Japan suggests that work stressors, such as job strain and long working hours, are associated with a moderately elevated risk of incident coronary heart disease and stroke. The excess risk for exposed individuals is 10-40 % compared with those free of such stressors. Differences between men and women, younger versus older employees and workers from different socioeconomic backgrounds appear to be small, indicating that the association is robust. Meta-analyses of a wider range of health outcomes show additionally an association between work stress and type 2 diabetes, though not with common cancers or chronic obstructive pulmonary disease, suggesting outcome specificity. Few studies have addressed whether mitigation of work stressors would reduce the risk of cardiovascular disease. In view of the limited interventional evidence on benefits, harms and cost-effectiveness, definitive recommendations have not been made (e.g. by the US Preventive Services Taskforce) for the primary prevention of cardiovascular disease via workplace stress reduction. Nevertheless, governments are already launching healthy workplace campaigns, and preventing excessive work stress is a legal obligation in several countries. Promoting awareness of the link between stress and health among both employers and workers is an important component of workplace health promotion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.