ArticleScientific reports2015
Vitroprocines, new antibiotics against Acinetobacter baumannii, discovered from marine Vibrio sp. QWI-06 using mass-spectrometry-based metabolomics approach.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Genomic and spectroscopic analysis for antimicrobial metabolite profiling of Microbacterium testaceum endophyte.AMB Express · 2026Article
- Marine Bacteria as a Source of Antibiotics AgainstMarine drugs · 2026Review
- Last Decade Insights in Exploiting Marine Microorganisms as Sources of New Bioactive Natural Products.Marine drugs · 2025Review
- The Exploration of Microbial Natural Products and Metabolic Interaction Guided by Mass Spectrometry Imaging.Bioengineering (Basel, Switzerland) · 2022Review
- Metabolomics on the study of marine organisms.Metabolomics : Official journal of the Metabolomic Society · 2022Review
- Recent Advances in Discovery of Lead Structures from Microbial Natural Products: Genomics- and Metabolomics-Guided Acceleration.Molecules (Basel, Switzerland) · 2021Review
- Comparative Metabologenomics Analysis of Polar Actinomycetes.Marine drugs · 2021Article
- Identification and dereplication of endophytic Colletotrichum strains by MALDI TOF mass spectrometry and molecular networking.Scientific reports · 2020Article
- Integrating Molecular Network and Culture Media Variation to Explore the Production of Bioactive Metabolites byMarine drugs · 2019Article
- Genome and metabolome mining of marine obligate Salinisporsatrains to discover new natural products.Turkish journal of biology = Turk biyoloji dergisi · 2019Article
- Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains.MicrobiologyOpen · 2017Article
- Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols.Journal of natural products · 2017Article
- 5-Episinuleptolide Decreases the Expression of the Extracellular Matrix in Early Biofilm Formation of Multi-Drug Resistant Acinetobacter baumannii.Marine drugs · 2016Article
- Article
- Current status and contemporary approaches to the discovery of antitumor agents from higher plants.Biotechnology advancesReview
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8 authors.
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Abstract
A robust and convenient research strategy integrating state-of-the-art analytical techniques is needed to efficiently discover novel compounds from marine microbial resources. In this study, we identified a series of amino-polyketide derivatives, vitroprocines A-J, from the marine bacterium Vibrio sp. QWI-06 by an integrated approach using imaging mass spectroscopy and molecular networking, as well as conventional bioactivity-guided fractionation and isolation. The structure-activity relationship of vitroprocines against Acinetobacter baumannii is proposed. In addition, feeding experiments with (13)C-labeled precursors indicated that a pyridoxal 5'-phosphate-dependent mechanism is involved in the biosynthesis of vitroprocines. Elucidation of amino-polyketide derivatives from a species of marine bacteria for the first time demonstrates the potential of this integrated metabolomics approach to uncover marine bacterial biodiversity.
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