Evidence map›Paper›PMID 26238310›Full record

ArticleMolecular medicine reports2015

Determination of ABO blood group genotypes using the real‑time loop‑mediated isothermal amplification method.

Chao Zhang, Juanli Zhu, Jiangcun Yang, Yinsheng Wan, Ting Ma, Yali Cui

Abstract read
In one paragraph

Article in Molecular medicine reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao ZhangCollege of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, P.R. China.
Juanli ZhuCollege of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, P.R. China.
Jiangcun YangDepartment of Transfusion Medicine, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi 710068, P.R. China.
Yinsheng WanDepartment of Biology, Providence College, Providence, RI 02918, USA.
Ting MaCollege of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, P.R. China.
Yali CuiCollege of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, P.R. China.

Funding

UNDERGRADUATE RESEARCH AND SEMINARSP20RR016457 · NCRR · UNIVERSITY OF RHODE ISLAND · PI SHAKARIAN, ALISON M · 2001 to 2011
$35.5M
NCRR NIH HHS P20 RR016457NCRR NIH HHS P20RR016457
6 · The paper itself

Abstract

ABO genotyping is commonly used in several situations, including blood transfusion, personal identification and disease detection. The present study developed a novel method for ABO genotyping, using loop‑mediated isothermal amplification (LAMP). This method allows the simultaneous determination of six ABO genotypes under 40 min at a constant temperature of 62˚C. The genotypes of 101 blood samples were determined to be AA (n=6), AO (n=38), BB (n=12), BO (n=29), AB (n=8) and OO (n=8) by the LAMP assay. The results were compared with the phenotypes determined by serological assay and the genotypes determined by direct sequencing, and no discrepancies were observed. This novel and rapid method, with good accuracy and reasonably cost effective, provides a supplement to routine serological ABO typing and may also be useful in other point‑of‑care testing.

Indexed as

AllelesGenotypeABO Blood-Group SystemHumansReal-Time Polymerase Chain ReactionABO Blood-Group System

Identifiers

PMID26238310
PMCPMC4581819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.