Evidence map›Paper›PMID 26238262›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2015

Mouse Genome Informatics (MGI): reflecting on 25 years.

Janan T Eppig, Joel E Richardson, James A Kadin, Martin Ringwald, Judith A Blake, Carol J Bult

Abstract readHistorical ArticleReview
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. GMMID: genetically modified mice information database.Database : the journal of biological databases and curation · 2024
    Article
  6. Generation and analysis of a mouse multi-tissue genome annotation atlas.bioRxiv : the preprint server for biology · 2024
    Article
  7. Review
  8. Genetic and Molecular Quality Control of Genetically Engineered Mice.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Proteomic Analysis ofMolecular & cellular proteomics : MCP · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janan T EppigMouse Genome Informatics, The Jackson Laboratory, Bar Harbor, ME, 04609, USA, janan.eppig@jax.org.
Joel E Richardson
James A Kadin
Martin Ringwald
Judith A Blake
Carol J Bult

Funding

SOFTWARE AND DATABASE SYSTEM DEVELOPMENTP41HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1995 to 2010
$72.1M
Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Mark D ADAMS · 1985 to 2026
$61.9M
Mouse Genome DatabaseU41HG000330 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A, BULT, CAROL J · 2011 to 2020
$45.5M
Technical DevelopmentP41HD062499 · NICHD · JACKSON LABORATORY · PI MARTIN RINGWALD · 2011 to 2026
$37.3M
Mouse Models of Human Cancer DatabaseR01CA089713 · NCI · JACKSON LABORATORY · PI BULT, CAROL J · 2002 to 2025
$17.5M
PRO: A Protein Ontology in Open Biomedical OntologiesR01GM080646 · NIGMS · UNIVERSITY OF DELAWARE · PI WU, CATHY H. · 2007 to 2018
$8.9M
CRE Driver Strain ResourcesR24OD011190 · OD · JACKSON LABORATORY · PI MURRAY, STEPHEN A, SMITH, CYNTHIA LOUISE · 2012 to 2022
$7.9M
InterMOD: integrated data and tools to support model organism researchR01HG004834 · NHGRI · UNIVERSITY OF CAMBRIDGE · PI CHERRY, J. MICHAEL, MICKLEM, GOS · 2009 to 2013
$2.8M
MULTI-LEVEL ANALYSIS AND DISPLAY OF MOUSE GENOME DATAP01HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1990 to 1994
–
NCI NIH HHS CA089713NCI NIH HHS P30 CA034196NCI NIH HHS R01 CA089713NHGRI NIH HHS HG000330NHGRI NIH HHS HG004834NHGRI NIH HHS P41 HG000330NHGRI NIH HHS R01 HG004834NHGRI NIH HHS U41 HG000330NICHD NIH HHS HD062499NICHD NIH HHS P41 HD062499NIGMS NIH HHS GM080646NIGMS NIH HHS R01 GM080646NIH HHS OD011190NIH HHS R24 OD011190
6 · The paper itself

Abstract

From its inception in 1989, the mission of the Mouse Genome Informatics (MGI) resource remains to integrate genetic, genomic, and biological data about the laboratory mouse to facilitate the study of human health and disease. This mission is ever more feasible as the revolution in genetics knowledge, the ability to sequence genomes, and the ability to specifically manipulate mammalian genomes are now at our fingertips. Through major paradigm shifts in biological research and computer technologies, MGI has adapted and evolved to become an integral part of the larger global bioinformatics infrastructure and honed its ability to provide authoritative reference datasets used and incorporated by many other established bioinformatics resources. Here, we review some of the major changes in research approaches over that last quarter century, how these changes are reflected in the MGI resource you use today, and what may be around the next corner.

Indexed as

GenomeSoftwareAnimalsDatabases, GeneticDisease Models, AnimalGenomicsGenotypeHistory, 20th CenturyHistory, 21st CenturyHumansMiceMutagenesis, Site-DirectedPhenotypeReverse Genetics

Identifiers

PMID26238262
PMCPMC4534491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.