Evidence map›Paper›PMID 26238051›Full record

ReviewAdvances in experimental medicine and biology2015

Monitoring Spiking Activity of Many Individual Neurons in Invertebrate Ganglia.

W N Frost, C J Brandon, A M Bruno, M D Humphries, C Moore-Kochlacs, T J Sejnowski, J Wang, E S Hill

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

W N FrostDepartment of Cell Biology and Anatomy, The Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL, 60064, USA, william.frost@rosalindfranklin.edu.
C J Brandon
A M Bruno
M D Humphries
C Moore-Kochlacs
T J Sejnowski
J Wang
E S Hill

Funding

Imaging circuit structure and memories in a multifunctional networkR01NS060921 · NINDS · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI FROST, WILLIAM · 2009 to 2011
$1.1M
Rapid Network Reorganization With LearningF31NS079036 · NINDS · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI BRUNO, ANGELA · 2012 to 2014
$103k
Howard Hughes Medical InstituteMedical Research CouncilNINDS NIH HHS F31 NS079036NINDS NIH HHS F31NS079036NINDS NIH HHS NS060921NINDS NIH HHS R01 NS060921
6 · The paper itself

Abstract

Optical recording with fast voltage sensitive dyes makes it possible, in suitable preparations, to simultaneously monitor the action potentials of large numbers of individual neurons. Here we describe methods for doing this, including considerations of different dyes and imaging systems, methods for correlating the optical signals with their source neurons, procedures for getting good signals, and the use of Independent Component Analysis for spike-sorting raw optical data into single neuron traces. These combined tools represent a powerful approach for large-scale recording of neural networks with high temporal and spatial resolution.

Indexed as

Action PotentialsAnimalsFluorescent DyesGanglia, InvertebrateImage Processing, Computer-AssistedLeechesNerve NetNeuronsSpatio-Temporal AnalysisSynapsesTritonia Sea SlugVoltage-Sensitive Dye ImagingFluorescent Dyes

Identifiers

PMID26238051
PMCPMC4560204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.