ReviewJournal of clinical medicine2014
Hyponatremia: Special Considerations in Older Patients.
Review in Journal of clinical medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Risk of antidepressant-induced hyponatremia in geriatric patients: a systematic review and meta-analysis.BMC geriatrics · 2026Pooled it
- Article
- Hyponatremia: Evolving diagnostics and emerging therapeutics in clinical practice.World journal of nephrology · 2026Review
- A drug-based model to predict hyponatremia in outpatients of a geriatric clinic.European journal of clinical pharmacology · 2025Article
- Article
- Challenging cases of hyponatremia incorrectly interpreted by ChatGPT.BMC medical education · 2025Article
- An Instant Relationship Between Hyponatremia, Geriatric Syndromes, and Drugs in Older Adults: A Cross-Sectional Analysis from a Single Geriatric Clinic.Diagnostics (Basel, Switzerland) · 2025Article
- Serum sodium levels and geriatric syndromes: an overlooked association.European geriatric medicine · 2025Article
- Article
- CARDS, a Novel Prognostic Index for Risk Stratification and In-Hospital Monitoring.Journal of clinical medicine · 2024Article
- Effect of preparation method for radioactive iodine therapy on serum electrolytes.Japanese journal of radiology · 2023Article
- A Case-Control Study of Cognitive Function in Patients with End-Stage Renal Disease Before and After Hemodialysis in Southern Spain.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Prospective, multicentre study of screening, investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland.Stroke and vascular neurology · 2023Review
- The Association between Dysnatraemia during Hospitalisation and Post-COVID-19 Mental Fatigue.Journal of clinical medicine · 2023Article
- Diagnostic Workup and Outcome in Patients with Profound Hyponatremia.Journal of clinical medicine · 2023Article
- Increased Mortality in Elderly Patients Admitted with Hyponatremia: A Prospective Cohort Study.Journal of clinical medicine · 2021Article
- Serum sodium in relation to various domains of cognitive function in the elderly US population.BMC geriatrics · 2021Article
- A narrative review of progress in diagnosis and treatment of small cell lung cancer patients with hyponatremia.Translational lung cancer research · 2020Review
- Medication-related harm in older adults following hospital discharge: development and validation of a prediction tool.BMJ quality & safety · 2020Article
- Novel Diagnostic Tools for Identifying Cognitive Impairment in Dogs: Behavior, Biomarkers, and Pathology.Frontiers in veterinary science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyponatremia is especially common in older people. Recent evidence highlights that even mild, chronic hyponatremia can lead to cognitive impairment, falls and fractures, the latter being in part due to bone demineralization and reduced bone quality. Hyponatremia is therefore of special significance in frail older people. Management of hyponatremia in elderly individuals is particularly challenging. The underlying cause is often multi-factorial, a clear history may be difficult to obtain and clinical examination is unreliable. Established treatment modalities are often ineffective and carry considerable risks, especially if the diagnosis of underlying causes is incorrect. Nevertheless, there is some evidence that correction of hyponatremia can improve cognitive performance and postural balance, potentially minimizing the risk of falls and fractures. Oral vasopressin receptor antagonists (vaptans) are a promising innovation, but evidence of their safety and effect on important clinical outcomes in frail elderly individuals is limited.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.