Evidence map›Paper›PMID 26237483›Full record

ArticleJournal of clinical medicine2014

Health Resource Utilization Associated with Skeletal-Related Events in Patients with Advanced Prostate Cancer: A European Subgroup Analysis from an Observational, Multinational Study.

Amit Bahl, Herbert Hoefeler, Ignacio Duran, Guy Hechmati, Cristina Garzon-Rodriguez, John Ashcroft, Vito Lorusso, Prayashi Ghelani, Rachel Wei, Emma Thomas and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 6 countries.

Amit BahlUniversity Hospitals Bristol, Bristol Royal Infirmary, Upper Maudlin St., Bristol, Avon BS2 8HW, UK. amit.bahl@uhbristol.nhs.uk.
Herbert HoefelerResearch Centre Ruhr, Pferdebach Street 30, Witten 58455, Germany. hoefeler@forschungszentrum-ruhr.de.
Ignacio DuranIntegrated Cancer Centre Clara Campal (CIOCC), Calle Oña 10, Madrid 28050, Spain. ignacioduranmartinez@gmail.com.
Guy HechmatiHealth Economics, Amgen (Europe) GmbH, Dammstrasse 23, Zug 6301, Switzerland. hechmati@amgen.com.
Cristina Garzon-RodriguezInstitute of Oncology Catalá ICO-IDIBELL, Avenue Gran Via de l'Hospitalet, 199-203, Hospitalet de Llobregat, Barcelona 08908, Spain. cgrodriguez@iconcologia.net.
John AshcroftPinderfields General Hospital, Mid Yorkshire Hospitals NHS Trust, Wakefield WF1 4DG, UK. john.ashcroft@midyorks.nhs.uk.
Vito LorussoNational Cancer Institute IRCCS Giovanni Paolo II, Viale Orazio Flacco 65, 70124, Bari, Italy. vitolorusso@inwind.it.
Prayashi GhelaniBiostatistics, Ovatech Solutions, 112 Morden Road Abbey, London SW19 2NA, UK. pghelani@amgen.com.
Rachel WeiBiostatistics, Amgen Inc., 1 Amgen Center Drive, Thousand Oaks, CA 91320, USA. gwei@amgen.com.
Emma ThomasScientific Publications, Amgen (Europe) GmbH, Dammstrasse 23, 6301 Zug, Switzerland. embooth@amgen.com.
Diana LüftnerCharité-University Medical Hospital Berlin, Charité Campus Benjamin Franklin, Charitéplatz 1, Berlin D-10117, Germany. hoefeler@forschungszentrum-ruhr.de.
Amgen (Switzerland) · CHAmgen (United States) · USBristol Royal Infirmary · GBCharité - Universitätsmedizin Berlin · DEInstitut d'Investigació Biomédica de Bellvitge · ESIstituto Tumori Bari · ITMid Yorkshire Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to increase the understanding of health resource utilization (HRU) associated with skeletal-related events (SREs) occurring in patients with bone metastases secondary to advanced prostate cancer. A total of 120 patients from Germany, Italy, Spain and the United Kingdom were enrolled in this observational study. They had bone metastases secondary to prostate cancer and had experienced at least one SRE in the 97 days before giving informed consent. HRU data were collected retrospectively for 97 days before enrolment and prospectively for up to 18-21 months. HRU, including the number and duration of inpatient hospitalizations, number of outpatient and emergency department visits and procedures, was independently attributed by investigators to an SRE. Of the 222 SREs included in this analysis, 26% were associated with inpatient stays and the mean duration per SRE was 21.4 days (standard deviation (SD) 17.8 days). Overall, 174 SREs (78%) required an outpatient visit and the mean number of visits per SRE was 4.6 (SD 4.6). All SREs are associated with substantial HRU. Preventing SREs in patients with advanced prostate cancer and bone metastases may help to reduce the burden to both patients and European healthcare systems.

Indexed as

bone metastasesEuropehealth resource utilizationprostate cancerskeletal-related events

Identifiers

PMID26237483
PMCPMC4449648
OpenAlexW2093997624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.