Evidence map›Paper›PMID 26237446›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2015

Tackling Cell Transplantation Anoikis: An Injectable, Shape Memory Cryogel Microcarrier Platform Material for Stem Cell and Neuronal Cell Growth.

Ben Newland, Petra B Welzel, Heike Newland, Claudia Renneberg, Petr Kolar, Mikhail Tsurkan, Anne Rosser, Uwe Freudenberg, Carsten Werner

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  15. A State-of-the-Art of Functional Scaffolds for 3D Nervous Tissue Regeneration.Frontiers in bioengineering and biotechnology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ben NewlandLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Petra B WelzelLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Heike NewlandLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Claudia RennebergLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Petr KolarLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Mikhail TsurkanLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Anne RosserBrain Repair Group, School of Biosciences, Cardiff University, Cardiff, CF10 3AX, Wales, UK.
Uwe FreudenbergLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.
Carsten WernerLeibniz Institute of Polymer Research Dresden (IPF), Max Bergmann Center of Biomaterials Dresden (MBC) and Technische Universität Dresden (TUD), Center for Regenerative Therapies Dresden (CRTD), Hohe Str. 6, 01069, Dresden, Germany.

Funding

Medical Research Council G1001257Medical Research Council MR/L010305/1Parkinson's UK K-1407Wellcome Trust
6 · The paper itself

Abstract

Highly macroporous semisynthetic cryogel microcarriers can be synthesized for culturing stem cells and neuronal type cells. Growth factors loaded to heparin-containing microcarriers show near zero-order release kinetics and cell-loaded microcarriers can be injected through a fine gauge cannula without negative effect on the cells. These carriers can be applied for cell transplantation applications.

Indexed as

Cell TransplantationMicrospheresAnimalsAnoikisCell MovementCell ProliferationCryogelsInjectionsNeuronsPC12 CellsRatsRats, TransgenicStem CellsCryogelsadherent matrixbiomaterialscryogelsheparinmicrocarriersneurotrophinshape memorystar-PEG

Identifiers

PMID26237446
PMCPMC5656175

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.