Evidence map›Paper›PMID 26237393›Full record

ArticleJournal of clinical medicine2014

It's More Than a Blood Test: Patients' Perspectives on Noninvasive Prenatal Testing.

Ruth M Farrell, Mary Beth Mercer, Patricia K Agatisa, Marissa B Smith, Elliot Philipson

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
8.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  4. Attitudes About NIPT Routinisation: A Report from a Qualitative Study of 20 UK Healthcare Professionals.Health care analysis : HCA : journal of health philosophy and policy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ruth M FarrellDepartment of Bioethics, Cleveland Clinic, 9500 Euclid Avenue JJ60, Cleveland, OH 44195, USA. farrelr@ccf.org.
Mary Beth MercerDepartment of Bioethics, Cleveland Clinic, 9500 Euclid Avenue JJ60, Cleveland, OH 44195, USA. mercerm@ccf.org.
Patricia K AgatisaDepartment of Bioethics, Cleveland Clinic, 9500 Euclid Avenue JJ60, Cleveland, OH 44195, USA. agatisp@ccf.org.
Marissa B SmithGenomic Medicine Institute, Cleveland Clinic Center for Personalized Genetic Healthcare, 9500 Euclid Avenue NE50, Cleveland, OH 44195, USA. smithm31@ccf.org.
Elliot PhilipsonDepartment of Obstetrics and Gynecology, Cleveland Clinic Women's Health Institute, 9500 Euclid Avenue A81, Cleveland, OH 44195, USA. philipe@ccf.org.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noninvasive prenatal testing (NIPT) offers pregnant women a new risk assessment tool for fetal aneuploidy that is superior to conventional screening tests. We conducted focus groups with women who were currently pregnant or had recently delivered in the past year to characterize their perspectives about NIPT and to explore factors they would consider during decision making about its use. Women identified accuracy, early timing, testing ease, and determination of fetal sex as advantages of NIPT over other screens, and the noninvasive method of NIPT as an advantage over diagnostic tests. False positive and false negative results, anxiety, cost and insurance coverage were seen as disadvantages of NIPT. Women who do not want fetal aneuploidy information most likely will not undergo NIPT, despite its advantages over other screening tests. However, given its advantages, the decision to have NIPT is straightforward for women who want genetic information about the fetus. Women emphasized the need to make autonomous, private, and informed choices about NIPT, as they would with any prenatal genetic testing option. These perspectives may guide clinicians to conduct effective and clinically relevant counseling with pregnant women who consider utilizing this new genetic technology.

Indexed as

noninvasive prenatal testingpatient decision makingpatients’ perspectives

Identifiers

PMID26237393
PMCPMC4449684
OpenAlexW1975810962

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.