ArticleArthritis care & research2016
Longitudinal Course of Physical Function in People With Symptomatic Knee Osteoarthritis: Data From the Multicenter Osteoarthritis Study and the Osteoarthritis Initiative.
Article in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Traditional Chinese Exercise in Treating Knee Osteoarthritis: A Systematic Review and Meta-Analysis.PloS one · 2017Pooled it
- Efficacy of Computer-Based Telephone Counseling on Long-Term Adherence to Strength Training in Elderly Patients With Knee Osteoarthritis: A Randomized Trial.Arthritis care & research · 2020Trial
- Lower Income and Nonheterosexual Orientation Are Associated With Poor Access to Care in Patients With Knee Osteoarthritis.Arthroplasty today · 2024Article
- Walking speeds are lower for short distance and turning locomotion: Experiments and modeling in low-cost prosthesis users.PloS one · 2024Article
- Exploring relationships among multi-disciplinary assessments for knee joint health in service members with traumatic unilateral lower limb loss: a two-year longitudinal investigation.Scientific reports · 2023Article
- Validating Knee Varus Alignment Measurements Using Markerless Motion Capture.Geriatrics (Basel, Switzerland) · 2023Article
- Patient-Reported Outcomes in Calcium Pyrophosphate Deposition Disease Compared to Gout and Osteoarthritis.The Journal of rheumatology · 2023Article
- Article
- Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway.Journal of orthopaedic surgery and research · 2023Article
- Psychometric validation of the Korean version of PROMIS 29 Profile V2.1 among patients with lower extremity problems.BMC sports science, medicine & rehabilitation · 2021Article
- Program evaluation of GLA:D® Australia: Physiotherapist training outcomes and effectiveness of implementation for people with knee osteoarthritis.Osteoarthritis and cartilage open · 2021Article
- Trajectories of Structural Disease Progression in Knee Osteoarthritis.Arthritis care & research · 2021Observational
- Weight Cycling and Knee Joint Degeneration in Individuals with Overweight or Obesity: Four-Year Magnetic Resonance Imaging Data from the Osteoarthritis Initiative.Obesity (Silver Spring, Md.) · 2021Article
- 10-Year natural course of early hip osteoarthritis in middle-aged persons with hip pain: a CHECK study.Annals of the rheumatic diseases · 2021Article
- Does the 1-year Decline in Walking Speed Predict Mortality Risk Beyond Current Walking Speed in Adults With Knee Osteoarthritis?The Journal of rheumatology · 2021Article
- A Single-Blinded Randomized Controlled Trial of Mesenchymal Stem Cell Therapy for the Treatment of Osteoarthritis of the Knee with Active Control.Journal of stem cells & regenerative medicine · 2021Article
- Symptomatic knee osteoarthritis is associated with worse but stable quality of life and physical function regardless of the compartmental involvement: Data from the OAI.Osteoarthritis and cartilage open · 2020Article
- The Association of an Increasing Waist Circumference and Risk of Incident Low Physical Function in Adults with Knee Osteoarthritis.The Journal of rheumatology · 2020Article
- The relationship of radiographic findings with pain, function, and quality of life in patients with knee osteoarthritis.Journal of clinical orthopaedics and trauma · 2020Article
- Patient-specific reference values for objective physical function tests: data from the Osteoarthritis Initiative.Clinical rheumatology · 2020Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectivePain and functional decline are hallmarks of knee osteoarthritis (OA). Nevertheless, longitudinal studies unexpectedly reveal stable or improved physical function. The aim of this study was to impute missing and pre-total knee replacement (TKR) values to describe physical function over time among people with symptomatic knee OA.
methodsWe included participants from the Multicenter Osteoarthritis Study (MOST) and the Osteoarthritis Initiative (OAI) with incident symptomatic knee OA, observed during the first 30 months in MOST and 36 months in OAI. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) physical function (WOMAC-PF), the 5-times sit-to-stand test, and the 20-meter-walk test were assessed at 4 and 5 years in MOST and at 6 years in OAI. We used a multiple imputation method for missing visits, and estimated pre-TKR values close to the time of TKR, using a fitted local regression smoothing curve. In mixed-effect models, we investigated the physical function change over time, using data before and after imputation and calculation of pre-TKR values.
resultsIn MOST, 225 (8%) had incident knee OA, with corresponding 577 (12.7%) in OAI. After adjusting for pre-TKR values and imputing missing values, we found that WOMAC-PF values remained stable or slightly declined over time, and the 20-meter-walk test results changed from stable in nonimputed analyses to worsening using imputed data.
conclusionData from MOST and OAI showed stable to worsening physical function over time in people with incident symptomatic knee OA after imputing missing values and adjusting pre-TKR values.
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