Evidence map›Paper›PMID 26236776›Full record

ArticleChronic obstructive pulmonary diseases (Miami, Fla.)

Identifying Patients with Undiagnosed COPD in Primary Care Settings: Insight from Screening Tools and Epidemiologic Studies.

MeiLan K Han, Anna W Steenrod, Elizabeth D Bacci, Nancy K Leidy, David M Mannino, Byron M Thomashow, R G Barr, Barry J Make, Russ P Bowler, Stephen I Rennard and 5 more

Abstract read
In one paragraph

Article in Chronic obstructive pulmonary diseases (Miami, Fla.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prediction models for the development of COPD: a systematic review.International journal of chronic obstructive pulmonary disease · 2018
    Pooled it
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  14. Efficacy of a Self-Designed Questionnaire for Community Screening of COPD.International journal of chronic obstructive pulmonary disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

MeiLan K HanUniversity of Michigan, Ann Arbor.
Anna W SteenrodEvidera, Bethesda, Maryland.
Elizabeth D BacciEvidera, Bethesda, Maryland.
Nancy K LeidyEvidera, Bethesda, Maryland.
David M ManninoUniversity of Kentucky, Lexington.
Byron M ThomashowColumbia University, New York, New York.
R G BarrColumbia University, New York, New York.
Barry J MakeNational Jewish Health, Denver, Colorado.
Russ P BowlerNational Jewish Health, Denver, Colorado.
Stephen I RennardUniversity of Nebraska, Omaha.
Julia F HoufekUniversity of Nebraska, Omaha.
Barbara P YawnOlmsted Medical Center, Rochester, Minnesota.
Catherine A MeldrumUniversity of Michigan, Ann Arbor.
John W WalshCOPD Foundation, Washington, DC.
Fernando J MartinezWeill Cornell Medical Center, New York, New York.

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Design and Testing of tools to Identify individuals at high risk for COPD^ 73R01HL114055 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEIDY, NANCY KLINE, MANNINO, DAVID · 2012 to 2014
$2.4M
NCATS NIH HHS UL1 TR002384NHLBI NIH HHS R01 HL114055
6 · The paper itself

Abstract

objectiveChronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality, yet research suggests this disease is greatly underdiagnosed. This literature review sought to summarize the most common and significant variables associated with case-finding or missed cases of COPD to inform more effective and efficient detection of high-risk COPD patients in primary care.

methodsPubMed and EMBASE were searched for articles describing case-finding and epidemiologic research to detect or characterize new cases of COPD. International studies in primary and non-primary care settings, published in English from 2002-2014, were eligible for inclusion. Studies related to risk factors for development of COPD were excluded.

resultsOf the 33 studies identified and reviewed, 21 were case-finding or screening and 12 were epidemiological, including cross-sectional, longitudinal, and retrospective designs. A range of variables were identified within and across studies. Variables common to both screening and epidemiological studies included age, smoking status, and respiratory symptoms. Seven significant predictors from epidemiologic studies did not appear in screening tools. No studies targeted discovery of higher risk patients such as those with reduced lung function or risks for exacerbations.

conclusionVariables used to identify new cases of COPD or differentiate COPD cases and non-cases are wide- ranging, (from sociodemographic to self-reported health or health history variables), providing insight into important factors for case identification. Further research is underway to develop and test the best, smallest variable set that can be used as a screening tool to identify people with undiagnosed, high-risk COPD in primary care.

Indexed as

chronic obstructive pulmonary diseaseliterature reviewprimary carescreening

Identifiers

PMID26236776
PMCPMC4521771

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.