ArticleJournal of diabetes research2015
Current Smoking Dose-Dependently Associated with Decreased β-Cell Function in Chinese Men without Diabetes.
Article in Journal of diabetes research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Influence of Internet-Based Health Management on Control of Blood Glucose in Patients with Type 2 Diabetes: A Four-Year Longitudinal Study.Healthcare (Basel, Switzerland) · 2025Article
- Clinical research progress on β-cell dysfunction in T2DM development in the Chinese population.Reviews in endocrine & metabolic disorders · 2025Review
- Nutriomics and artificial intelligence nutrition obesity cohort (NAINOC): a design paper for a prospective cohort for nutrition and obesity research.Clinical hypertension · 2025Article
- Associations Between Alcohol Consumption and Cigarette Smoking and Insulin Secretion and Resistance in Vietnamese Men Without a History of Diabetes: A Cross-Sectional Study.Journal of diabetes research · 2025Article
- Clinical characteristics and complication risks in data-driven clusters among Chinese community diabetes populations.Journal of diabetes · 2024Article
- Central and peripheral actions of nicotine that influence blood glucose homeostasis and the development of diabetes.Pharmacological research · 2023Review
- Smoking causes the disorder of glucose metabolism under different levels of blood pressure in male occupational population.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Latent autoimmune diabetes in adults: a focus on β-cell protection and therapy.Frontiers in endocrinology · 2022Review
- Higher toenail selenium is associated with increased insulin resistance risk in omnivores, but not in vegetarians.Nutrition & metabolism · 2020Article
- Impact of cigarette smoking on the relationship between body mass index and insulin: Longitudinal observation from the Bogalusa Heart Study.Diabetes, obesity & metabolism · 2018Observational
- Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Type 2 Diabetes Mellitus.BioMed research international · 2018Article
- Assessing the impact of cigarette smoking on β-cell function and risk for type 2 diabetes in a non-diabetic Chinese cohort.American journal of translational research · 2018Article
- Substance Use Disorders among Patients with Type 2 Diabetes: a Dangerous but Understudied Combination.Current diabetes reports · 2017Review
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Authors and funding
12 authors.
Funding
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Abstract
The aim of this study was to evaluate the associations between chronic smoking and insulin resistance and β-cell function in Chinese men without diabetes. A total of 1,568 participants were recruited by multistage sampling. Using homeostatic model assessment (HOMA), geometric means of insulin resistance (HOMA-IR) and β-cell function (HOMA-β) with 95% confidence interval (CI) were calculated by general linear model. Odds ratios (ORs) with 95% CI were estimated to evaluate the associations between smoking status and insulin resistance and β-cell deficiency under a logistic regression model. Current smokers had higher levels of 2 h glucose (6.66 versus 6.48 mmol/L) for oral glucose tolerance test and lower levels of fasting insulin (5.68 versus 6.03 mU/L) than never smokers. The adjusted means for HOMA-β (%) were 54.86 in current smokers and 58.81 in never smokers (P = 0.0257). Current smoking was associated with β-cell deficiency (OR 1.29, 95% CI 1.01-1.64) compared to never smoking. The β-cell function gradually decreased with increasing smoking intensity (P trend = 0.0026), and the differences were statistically significant when the pack-year of smoking was 20 or above. No association was observed between smoking status and HOMA-IR. Our study suggested that chronic smoking may dose-dependently suppress insulin secretion in Chinese men.
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