ArticleBioMed research international2015
Preparative Purification of Liriodendrin from Sargentodoxa cuneata by Macroporous Resin.
Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Liriodendron attenuates intestinal fibrosis and inflammation in mice with radiation proctopathy.Chinese medicine · 2025Article
- Liriodendrin stimulates proliferation and milk protein synthesis of mammary epithelial cells via the PI3K-DDX18 signaling.In vitro cellular & developmental biology. Animal · 2024Article
- Protective Effects of Liriodendrin on Myocardial Infarction-Induced Fibrosis in RatsCombinatorial chemistry & high throughput screening · 2024Article
- Protective effect of liriodendrin on IgG immune complex-induced acute lung injury via inhibiting SRC/STAT3/MAPK signaling pathway: a network pharmacology research.Naunyn-Schmiedeberg's archives of pharmacology · 2023Article
- Glycosides as Potential Medicinal Components for Ulcerative Colitis: A Review.Molecules (Basel, Switzerland) · 2023Review
- Study on the protective effect and mechanism of Liriodendrin on radiation enteritis in mice.Journal of radiation research · 2022Article
- AnMetabolites · 2021Article
- Purification of 3, 4-dihydroxyphenylethyl alcohol glycoside from Sargentodoxa cuneata (Oliv.) Rehd. et Wils. and its protective effects against DSS-induced colitis.Scientific reports · 2019Article
- Protective Role of Liriodendrin in Sepsis-Induced Acute Lung Injury.Inflammation · 2016Article
- Simultaneous Determination of Four Active Ingredients in Sargentodoxa cuneata by HPLC Coupled with Evaporative Light Scattering Detection.International journal of analytical chemistry · 2016Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The preparative purification of liriodendrin from Sargentodoxa cuneata using macroporous resin combined with crystallization process was evaluated. The properties of adsorption/desorption of liriodendrin on eight macroporous resins were investigated systematically. X-5 resin was selected as the most suitable medium for liriodendrin purification. The adsorption of liriodendrin on X-5 resin fitted well with the pseudo-second-order kinetic model and Langmuir isotherm model. Dynamic adsorption/desorption tests were performed using a glass column packed with X-5 resin to optimize the separation process of liriodendrin. After one treatment with X-5 resin, the content of liriodendrin in the product was increased 48.73-fold, from 0.85% to 41.42%, with a recovery yield of 88.9%. 97.48% liriodendrin was obtained by further crystallization and determined by HPLC. The purified product possessed strong antioxidant activity. In conclusion, purification of liriodendrin might expend its further pharmacological researches and further applications in pharmacy.
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