Evidence map›Paper›PMID 26236566›Full record

ArticleCurrent pathobiology reports2015

Xenopus as a Model for GI/Pancreas Disease.

Matthew C Salanga, Marko E Horb

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current pathobiology reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Xenbase: Facilitating the Use ofFrontiers in physiology · 2019
    Review
  4. Review
  5. Research proceedings on amphibian model organisms.Dong wu xue yan jiu = Zoological research · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Matthew C SalangaNational Xenopus Resource, Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, 7 MBL St., Woods Hole, MA 02543, .
Marko E HorbNational Xenopus Resource, Eugene Bell Center for Regenerative Biology and Tissue Engineering, Marine Biological Laboratory, 7 MBL St., Woods Hole, MA 02543, .
Marine Biological Laboratory · US

Funding

Resource CoreP40OD010997 · OD · MARINE BIOLOGICAL LABORATORY · PI Marko E Horb · 2012 to 2026
$13.1M
Xenopus models of human disease by targeted genome editingR01HD084409 · NICHD · MARINE BIOLOGICAL LABORATORY · PI HORB, MARKO E · 2015 to 2019
$2.9M
Transcriptional Regulatory Networks Controlling Xenopus Pancreas DevelopmentR01DK077197 · NIDDK · MARINE BIOLOGICAL LABORATORY · PI HORB, MARKO E · 2007 to 2011
$1.1M
NICHD NIH HHS R01 HD084409NIDDK NIH HHS R01 DK077197NIH HHS P40 OD010997
6 · The paper itself

Abstract

Diseases affecting endodermal organs like the pancreas, lung and gastrointestinal (GI) tract have a substantial impact on human welfare. Since many of these are congenital defects that arise as a result of defects during development broad efforts are focused on understanding the development of these organs so as to better identify risk factors, disease mechanisms and therapeutic targets. Studies implementing model systems, like the amphibian Xenopus, have contributed immensely to our understanding of signaling (e.g. Wnt, FGF, BMP, RA) pathways and gene regulation (e.g.

Indexed as

diabetesendodermGI tractlungoocytepancreasXenopus

Identifiers

PMID26236566
PMCPMC4518857
OpenAlexW1978267381

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.