Evidence map›Paper›PMID 26236557›Full record

ArticleJournal of AIDS & clinical research2015

HIV Associated Chronic Obstructive Pulmonary Disease in Nigeria.

Maxwell O Akanbi, Babafemi O Taiwo, Chad J Achenbach, Obianuju B Ozoh, Daniel O Obaseki, Halima Sule, Oche O Agbaji, Christiana O Ukoli

Abstract read
In one paragraph

Article in Journal of AIDS & clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. HIV-associated lung disease.Nature reviews. Disease primers · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. An Emerging Syndemic of Smoking and Cardiopulmonary Diseases in People Living with HIV in Africa.International journal of environmental research and public health · 2021
    Article
  12. Article
  13. Chronic obstructive pulmonary disease in HIV.Expert review of respiratory medicine · 2021
    Review
  14. Lung function in men with and without HIV.AIDS (London, England) · 2020
    Observational
  15. Article
  16. Effects of commodity on the risk of emphysema in South African miners.International archives of occupational and environmental health · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maxwell O AkanbiDepartment of Medicine, Jos University Teaching Hospital, Jos, Nigeria.
Babafemi O TaiwoNorthwestern University Chicago, USA.
Chad J AchenbachNorthwestern University Chicago, USA.
Obianuju B OzohDepartment of Medicine, College of Medicine, University of Lagos, Lagos, Nigeria.
Daniel O ObasekiDepartment of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
Halima SuleDepartment of Family Medicine, Jos University Teaching Hospital, Nigeria.
Oche O AgbajiDepartment of Medicine, Jos University Teaching Hospital, Jos, Nigeria.
Christiana O UkoliDepartment of Medicine, Jos University Teaching Hospital, Jos, Nigeria.

Funding

Medical Education Partnership Initiative in NigeriaR24TW008878 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI ADEWOLE, ISAAC F, OLALEYE, DAVID OLUFEMI · 2010 to 2015
$9.4M
FIC NIH HHS R24 TW008878
6 · The paper itself

Abstract

objectiveTo determine the prevalence and risk factors for chronic obstructive pulmonary disease (COPD) among HIV-infected adults in Nigeria.

designCross-sectional study.

methodsHIV-infected adults aged ≥ 30 years with no acute ailments accessing care at the antiretroviral therapy clinic of Jos University Teaching Hospital were enrolled consecutively. Participants were interviewed to obtain pertinent demographic and clinical information, including exposure to risk factors for COPD. Post-bronchodilator spirometry was carried out. HIV related information was retrieved from the clinic medical records. COPD case-definition was based on the Global Initiative for Obstructive Lung Disease (GOLD) criteria using post-bronchodilator FEV

resultsStudy population comprised 356 HIV infected adults with mean age of 44.5 (standard deviation, 7.1) years and 59% were female. The mean time elapsed since HIV diagnosis was 7.0 (SD, 2.6) years and 97.5% of the respondents were on stable ART with virologic suppression present in 67.2%. Prevalence of COPD were 15.4% (95% confidence interval [CI] 11.7-19.2), 12.07% (95% CI 8.67-15.48), 22.19% (95% CI 18.16-26.83) using GOLD, ERS LLN and GLI LLN diagnostic criteria respectively. In multivariate analyses adjusting for gender, exposure to cigarette smoke or biomass, history of pulmonary tuberculosis, use of antiretroviral therapy, current CD4 T-cell count and HIV RNA, only age > 50 years was independently associated with COPD with OR 3.4; 95% CI 1.42-8.17 when compared to ages 30-40 years.

conclusionHIV-associated COPD is common in our population of HIV patients.

Indexed as

AfricaCOPDHIVLung diseaseNigeriaSpirometry

Identifiers

PMID26236557
PMCPMC4521629

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.