SynthesisPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2015
Dust mite avoidance for the primary prevention of atopic dermatitis: A systematic review and meta-analysis.
Synthesis in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- What are the highest yielding search strategy terms for systematic reviews in atopic dermatitis? A systematic review.Archives of dermatological research · 2021Pooled it
- Geographic pattern of asthma prevalence in Brazilian adolescents: a systematic review with meta-analysis.Jornal de pediatriaPooled it
- Consensus-Based Guidelines for the Treatment of Atopic Dermatitis in Korea (Part I): Basic Therapy, Topical Therapy, and Conventional Systemic Therapy.Annals of dermatology · 2025Article
- Prevention of Atopic Dermatitis: What Are We Missing?Allergy, asthma & immunology research · 2025Review
- Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.The Journal of allergy and clinical immunology · 2025Review
- Allergens in Atopic Dermatitis.Clinical reviews in allergy & immunology · 2025Review
- Effective Ways to Prevent Allergic Diseases: Where Do We Stand?Handbook of experimental pharmacology · 2022Article
- Current Insights into Atopic March.Children (Basel, Switzerland) · 2021Review
- Effect of environmental exposures on allergen sensitization and the development of childhood allergic diseases: A large-scale population-based study.The World Allergy Organization journal · 2021Article
- The evidence for interventions in early childhood allergy prevention - towards a living systematic review: protocol.F1000Research · 2021Article
- The Role of Environmental Exposures in Atopic Dermatitis.Current allergy and asthma reports · 2020Review
- Mite allergy and atopic dermatitis: Is there a clear link? (Review).Experimental and therapeutic medicine · 2020Review
- Under-diagnosis of atopic dermatitis in Puerto Rican children.The World Allergy Organization journal · 2019Article
- Molecular aspects of allergens in atopic dermatitis.Current opinion in allergy and clinical immunology · 2017Review
- The Skin as a Route of Allergen Exposure: Part I. Immune Components and Mechanisms.Current allergy and asthma reports · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDust mite sensitization plays a controversial role in the development of atopic dermatitis. Despite a lack of evidence for its efficacy, dust mite avoidance is commonly recommended for the prevention and treatment of atopic dermatitis. We aimed to evaluate whether dust mite avoidance strategies reduce the risk of developing atopic dermatitis in high-risk infants compared to randomized controls.
methodsStudies were obtained by searching MEDLINE, PubMed, Scopus, The Cochrane Library, and The Global Resource of Eczema Trials databases. We included randomized, controlled trials of high-risk infants treated with a dust mite avoidance intervention and assessed for atopic dermatitis. Data were extracted independently by two reviewers using predefined criteria.
resultsSeven randomized controlled trials met our inclusion criteria (total n = 3040). Studies were largely unblinded but otherwise of reasonable quality. Three trials utilizing a dust mite avoidance approach but not additional interventions were combined in a meta-analysis. Dust mite avoidance provided no benefit in the prevention of atopic dermatitis (relative risk (RR) = 1.08, 95% confidence interval (CI) = 0.78-1.49, I(2) = 73%).
conclusionsDust mite avoidance strategies alone or in combination with additional allergen avoidance modalities do not decrease the risk of developing atopic dermatitis and, given the current state of the evidence, should not be recommended for this purpose. The utility of dust mite avoidance for the treatment of atopic dermatitis or for the prevention and treatment of asthma or seasonal rhinoconjunctivitis are outside the scope of this review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.