Evidence map›Paper›PMID 26235143›Full record

ArticleThe British journal of radiology2015

A comparison of high b-value vs standard b-value diffusion-weighted magnetic resonance imaging at 3.0 T for medulloblastomas.

Chengkun Han, Long Zhao, Shan Zhong, Xiurong Wu, Jianfeng Guo, Xiongjie Zhuang, Haiwei Han

Open access · greenAbstract readComparative Study
In one paragraph

Article in The British journal of radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chengkun Han1 Department of Neuroradiology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Long Zhao2 Department of Nuclear Medicine & Minnan PET Center, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Shan Zhong3 Department of Pathology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Xiurong Wu1 Department of Neuroradiology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Jianfeng Guo4 Department of Neurosurgery, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Xiongjie Zhuang1 Department of Neuroradiology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Haiwei Han1 Department of Neuroradiology, The First Affiliated Hospital of Xiamen University, Xiamen, China.
First Affiliated Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the utility of diffusion-weighted (DW) MRI using high b-value vs standard b-value for patients with medulloblastoma (MB). Minimum apparent diffusion coefficient (ADCMIN) values were also compared with tumour cellularity.

methodsHigh and standard b-value DW images were obtained for 17 patients with MB. The number and location of the lesions, signal intensities (SIs), signal-to-noise ratios (SNRs), contrast-to-noise ratios, contrast ratios (CRs) and ADCs of the lesions were compared. Tumour cellularity was also measured and compared with ADCMIN values.

resultsAll 20 lesions were hyperintense on the DW MR images with high and standard b-values. Four additional lesions were revealed on high b-value, and all 24 lesions were more conspicuous at high b-value. SI, SNR and ADC values for the lesions were lower in the high b-value images than in the standard b-value images. The ADCMIN value at b = 3000 s mm(-2) was more significantly associated with tumour cellularity than that at b = 1000 s mm(-2). CR values were significantly higher in the high b-value images than in the standard b-value images.

conclusionDW imaging using high b-value may be beneficial for detecting additional, less prominent lesions and may improve the contrast between MB lesions and normal tissue. A stronger inverse correlation with tumour cellularity was identified using the ADCMIN values at high b-value. ADVANCES IN KNOWLEDGE: This study demonstrates the superiority of high b-value DW imaging compared with standard b-value imaging for the detection of MB lesions, especially those with subtle foci.

Indexed as

Diffusion Magnetic Resonance ImagingAdolescentCerebellar NeoplasmsCerebellumChildChild, PreschoolFemaleHumansImage Interpretation, Computer-AssistedInfantMaleMedulloblastomaReproducibility of ResultsRetrospective StudiesSensitivity and SpecificitySignal-To-Noise Ratio

Identifiers

PMID26235143
PMCPMC4730971
OpenAlexW1091326591

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.