Evidence map›Paper›PMID 26234464›Full record

ArticleArtificial intelligence in medicine2015

Synthesis of a high resolution social contact network for Delhi with application to pandemic planning.

Huadong Xia, Kalyani Nagaraj, Jiangzhuo Chen, Madhav V Marathe

Abstract read
In one paragraph

Article in Artificial intelligence in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Epidemic dynamics in census-calibrated modular contact network.Network modeling and analysis in health informatics and bioinformatics · 2023
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huadong XiaNetwork Dynamics & Simulation Science Laboratory, Virginia Bioinformatics Institute, Virginia Tech, 1880 Pratt Drive, Blacksburg, VA 24060, United States.
Kalyani NagarajNetwork Dynamics & Simulation Science Laboratory, Virginia Bioinformatics Institute, Virginia Tech, 1880 Pratt Drive, Blacksburg, VA 24060, United States.
Jiangzhuo ChenNetwork Dynamics & Simulation Science Laboratory, Virginia Bioinformatics Institute, Virginia Tech, 1880 Pratt Drive, Blacksburg, VA 24060, United States.
Madhav V MaratheNetwork Dynamics & Simulation Science Laboratory, Virginia Bioinformatics Institute, Virginia Tech, 1880 Pratt Drive, Blacksburg, VA 24060, United States. Electronic address: mmarathe@vbi.vt.edu.

Funding

Synthetic Information Systems for Better Informing Public Health PolicymakersU01GM070694 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI EUBANK, STEPHEN G, MARATHE, MADHAV VISHNU · 2004 to 2016
$8.6M
Systems Analysis of Social Pathways of Epidemics to Reduce Health DisparitiesR01GM109718 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MARATHE, ACHLA, VULLIKANTI, ANIL · 2014 to 2022
$3.6M
NIGMS NIH HHS 5U01GM070694-11NIGMS NIH HHS R01 GM109718NIGMS NIH HHS U01 GM070694
6 · The paper itself

Abstract

objectiveWe aim to understand quantitatively how targeted-layered containment (TLC) strategies contain an influenza pandemic in a populous urban area such as Delhi, India using networked epidemiology.

methodsA key contribution of our work is a methodology for the synthesis of a realistic individual-based social contact network for Delhi using a wide variety of open source and commercial data. New techniques were developed to infer daily activities for individuals using aggregate data published in transportation science literature in combination with human development surveys and targeted local surveys. The resulting social contact network is the first such network constructed for any urban region of India. This time varying, spatially explicit network has over 13 million people and more than 200 million people-people contacts. The network has several interesting similarities and differences when compared with similar networks of US cities. Additionally, we use a high performance agent-based modeling environment to study how an influenza-like illness would spread over Delhi. We also analyze well understood pharmaceutical and non-pharmaceutical containment strategies, or a combination thereof (also known as TLCs), to control a pandemic outbreak.

results(i) TLC strategies produce the mildest and most delayed epidemic out-break than any of the individual interventions; (ii) the epidemic dynamics of Delhi appear to be strongly influenced by the activity patterns and the demographic structure of its local residents; and (iii) a high resolution social contact network helps in analyzing effective public health policies.

conclusionA high resolution synthetic network is constructed based on surveyed data. It captures the underlying contact structure of a certain population and can be used to quantitatively analyze public health policy effectiveness. To the best of our knowledge, this study is the first of its kind in the Indian sub-continent.

Indexed as

Disaster PlanningPandemicsHumansIndiaImputation techniquesIterative proportional fittingLabeled graphletsNetworked-epidemiologyPandemic responseSynthetic populationTargeted-layered containment

Identifiers

PMID26234464
PMCPMC4605857

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.