Evidence map›Paper›PMID 26234160›Full record

ReviewSocial neuroscience2015

Parental buffering of fear and stress neurobiology: Reviewing parallels across rodent, monkey, and human models.

Megan R Gunnar, Camelia E Hostinar, Mar M Sanchez, Nim Tottenham, Regina M Sullivan

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Social neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04107506 (RCT of FIND Video Coaching Intervention for Caregivers Facing Economic Adversity), which is not on this map. Cited by 94 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04107506 nacompletednot on this mapstarted 2019, after this paper: background citation

RCT of FIND Video Coaching Intervention for Caregivers Facing Economic Adversity

TypeinterventionalSponsorUniversity of OregonRan2019 to 2025Enrolled160ConditionsChild Behavior, Parent-Child RelationsArmsFilming Interactions to Nurture Development, The Healthy Toddler Program
3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 1 synthesis or guideline pooled it, 156 citations in OpenAlex.

  1. Pooled it
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  15. Emotional Availability as a Moderator of Stress for Young Children and Parents in Two Diverse Early Head Start Samples.Prevention science : the official journal of the Society for Prevention Research · 2025
    Article
  16. An Integrated Review of Findings from the Early Head Start University Partnerships Buffering Toxic Stress Consortium.Prevention science : the official journal of the Society for Prevention Research · 2025
    Review
  17. Review
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  19. Article
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Megan R Gunnara Institute of Child Development , University of Minnesota , Minneapolis , MN , USA.
Camelia E Hostinarb Institute for Policy Research , Northwestern University , Evanston , IL , USA.
Mar M Sanchezc Department of Psychiatry and Yerkes National Primate Research Center , Emory University , Atlanta , GA , USA.
Nim Tottenhamd Department of Psychology , Columbia University , New York , NY , USA.
Regina M Sullivane Emotional Brain Institute, Nathan S. Kline Institute for Psychiatric Research , Orangeburg , SC , USA.
Columbia University · USEmory University · USNathan Kline Institute for Psychiatric Research · USNorthwestern University · USUniversity of Minnesota · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
YNPRC NHP CLINICAL MEDICINE RESIDENCY PROGRAM - SUPPLEMENTP51RR000165 · NCRR · EMORY UNIVERSITY · PI ALTMAN, JOHN DAVID · 1985 to 2011
$114.0M
Project 3: The neurobiology of adverse early care in rhesus infants....P50MH078105 · NIMH · UNIVERSITY OF MINNESOTA · PI SANCHEZ, MAR M · 2009 to 2013
$9.9M
Predicting Heterogeneous Neurodevelopmental Outcomes in School-age Children with Early Caregiving AdversitiesR01MH091864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MILHAM, MICHAEL PETER, TOTTENHAM, NIM · 2010 to 2022
$5.1M
Maternal Influence Over Prefrontal Cortex and Transition to Independence - Revision - 2R37HD083217 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SULLIVAN, REGINA MARIE · 2015 to 2024
$4.7M
Stress and obesity synergize to impair neurobehavioral development in femalesR01HD077623 · NICHD · EMORY UNIVERSITY · PI SANCHEZ, MAR M, WILSON, MARK E · 2013 to 2017
$3.5M
Early life stress and adolescent cocaine abuse: neurobiological vulnerabilitiesR01DA038588 · NIDA · EMORY UNIVERSITY · PI SANCHEZ, MAR M · 2014 to 2020
$3.5M
Sensitive Period for Neurobehavioral Development of Social BehaviorR01MH091451 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SULLIVAN, REGINA MARIE · 2010 to 2014
$2.0M
Ontogeny of Olfactory Hedonic EncodingR01DC009910 · NIDCD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SULLIVAN, REGINA MARIE · 2009 to 2013
$1.7M
Neurobiology of Cognitive Functioning in InfancyR01HD033402 · NICHD · UNIVERSITY OF OKLAHOMA NORMAN · PI SULLIVAN, REGINA MARIE · 1995 to 2006
$1.3M
Understanding Neurodevelopment in Macaques with Different Rearing ExperiencesR21HD055255 · NICHD · EMORY UNIVERSITY · PI SANCHEZ, MAR M · 2007 to 2008
$461k
Self-regulation as a Health-Protective Factor in Adverse Socioeconomic ConditionsF32HD078048 · NICHD · NORTHWESTERN UNIVERSITY · PI HOSTINAR CAUDILL, CAMELIA E · 2014 to 2015
$92k
NCRR NIH HHS P51 RR000165NCRR NIH HHS P51RR000165NICHD NIH HHS F32 HD078048NICHD NIH HHS F32HD078048NICHD NIH HHS HD083217NICHD NIH HHS R01 HD033402NICHD NIH HHS R01 HD077623NICHD NIH HHS R01HD077623NICHD NIH HHS R21 HD055255NICHD NIH HHS R21HD055255NICHD NIH HHS R37 HD083217NIDA NIH HHS R01 DA038588NIDA NIH HHS R01DA038588NIDCD NIH HHS DC009910NIDCD NIH HHS R01 DC009910NIH HHS P51 OD011132NIH HHS P51OD1113NIMH NIH HHS MH091451NIMH NIH HHS P50 MH078105NIMH NIH HHS P50MH078105NIMH NIH HHS R01 MH091451NIMH NIH HHS R01 MH091864NIMH NIH HHS R01MH091864
6 · The paper itself

Abstract

It has been long recognized that parents exert profound influences on child development. Dating back to at least the seventeenth-century Enlightenment, the ability for parents to shape child behavior in an enduring way has been noted. Twentieth-century scholars developed theories to explain how parenting histories influence psychological development, and since that time, the number of scientific publications on parenting influences in both human and nonhuman animal fields has grown at an exponential rate, reaching numbers in the thousands by 2015. This special issue describes a symposium delivered by Megan Gunnar, Regina Sullivan, Mar Sanchez, and Nim Tottenham in the Fall of 2014 at the Society for Social Neuroscience. The goal of the symposium was to describe the emerging knowledge on neurobiological mechanisms that mediate parent-offspring interactions across three different species: rodent, monkey, and human. The talks were aimed at designing testable models of parenting effects on the development of emotional and stress regulation. Specifically, the symposium aimed at characterizing the special modulatory (buffering) effects of parental cues on fear- and stress-relevant neurobiology and behaviors of the offspring and to discuss examples of impaired buffering when the parent-infant relationship is disrupted.

Indexed as

Biological EvolutionFearNeurobiologyParent-Child RelationsStress, PsychologicalAnimalsHaplorhiniHumansParentsAmygdalaFearParentsPrefrontal cortexSocial bufferingStress

Identifiers

PMID26234160
PMCPMC5198892
OpenAlexW1896053654

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.