ArticleMedical physics2015
Three dimensional dose distribution comparison of simple and complex acquisition trajectories in dedicated breast CT.
Article in Medical physics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Cone-beam breast CT using an offset detector: effect of detector offset and image reconstruction algorithm.Physics in medicine and biology · 2022Article
- Motion artifacts assessment and correction using optical tracking in synchrotron radiation breast CT.Medical physics · 2021Article
- Radiation dosimetry of a clinical prototype dedicated cone-beam breast CT system with offset detector.Medical physics · 2021Article
- Cone beam CT multisource configurations: evaluating image quality, scatter, and dose using phantom imaging and Monte Carlo simulations.Physics in medicine and biology · 2020Article
- Applications of Computational Methods in Biomedical Breast Cancer Imaging Diagnostics: A Review.Journal of imaging · 2020Review
- Clinical Feasibility of Reduced Field-of-View Diffusion-Weighted Magnetic Resonance Imaging with Computed Diffusion-Weighted Imaging Technique in Breast Cancer Patients.Diagnostics (Basel, Switzerland) · 2020Article
- Shading artifact correction in breast CT using an interleaved deep learning segmentation and maximum-likelihood polynomial fitting approach.Medical physics · 2019Article
- Task-driven source-detector trajectories in cone-beam computed tomography: I. Theory and methods.Journal of medical imaging (Bellingham, Wash.) · 2019Article
- A dedicated breast-PET/CT scanner: Evaluation of basic performance characteristics.Medical physics · 2018Article
- Characterization of CT Hounsfield Units for 3D acquisition trajectories on a dedicated breast CT system.Journal of X-ray science and technology · 2018Article
- Implementation and CT sampling characterization of a third-generation SPECT-CT system for dedicated breast imaging.Journal of medical imaging (Bellingham, Wash.) · 2017Article
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Authors and funding
4 authors.
Funding
Abstract
purposeA novel breast CT system capable of arbitrary 3D trajectories has been developed to address cone beam sampling insufficiency as well as to image further into the patient's chest wall. The purpose of this study was to characterize any trajectory-related differences in 3D x-ray dose distribution in a pendant target when imaged with different orbits.
methodsTwo acquisition trajectories were evaluated: circular azimuthal (no-tilt) and sinusoidal (saddle) orbit with ±15° tilts around a pendant breast, using Monte Carlo simulations as well as physical measurements. Simulations were performed with tungsten (W) filtration of a W-anode source; the simulated source flux was normalized to the measured exposure of a W-anode source. A water-filled cylindrical phantom was divided into 1 cm(3) voxels, and the cumulative energy deposited was tracked in each voxel. Energy deposited per voxel was converted to dose, yielding the 3D distributed dose volumes. Additionally, three cylindrical phantoms of different diameters (10, 12.5, and 15 cm) and an anthropomorphic breast phantom, initially filled with water (mimicking pure fibroglandular tissue) and then with a 75% methanol-25% water mixture (mimicking 50-50 fibroglandular-adipose tissues), were used to simulate the pendant breast geometry and scanned on the physical system. Ionization chamber calibrated radiochromic film was used to determine the dose delivered in a 2D plane through the center of the volume for a fully 3D CT scan using the different orbits.
resultsMeasured experimental results for the same exposure indicated that the mean dose measured throughout the central slice for different diameters ranged from 3.93 to 5.28 mGy, with the lowest average dose measured on the largest cylinder with water mimicking a homogeneously fibroglandular breast. These results align well with the cylinder phantom Monte Carlo studies which also showed a marginal difference in dose delivered by a saddle trajectory in the central slice. Regardless of phantom material or filled fluid density, dose delivered by the saddle scan was negligibly different than the simple circular, no-tilt scans. The average dose measured in the breast phantom was marginally higher for saddle than the circular no tilt scan at 3.82 and 3.87 mGy, respectively.
conclusionsNot only does nontraditional 3D-trajectory CT scanning yield more complete sampling of the breast volume but also has comparable dose deposition throughout the breast and anterior chest volume, as verified by Monte Carlo simulation and physical measurements.
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