ArticleAmerican journal of hypertension2016
Relationship Between Carotid Atherosclerosis and Pulse Pressure with Renal Hemodynamics in Hypertensive Patients.
Article in American journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 35 citations in OpenAlex.
- Renal Resistive Index from Renal Hemodynamics to Cardiovascular Risk: Diagnostic, Prognostic, and Therapeutic Implications.Diseases (Basel, Switzerland) · 2025Review
- Renal Resistive Index and 10-Year Risk of Cardiovascular Disease Predicted by Framingham Risk Score and Pooled Cohort Equations: An Observational Study in Hypertensive Individuals Without Cardiovascular Disease.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025Observational
- Relationship Between 8-iso-prostaglandin-FLife (Basel, Switzerland) · 2025Article
- Relationship Between Renal Resistive Index and Retinal Vascular Density in Individuals with Hypertension.Biomedicines · 2025Article
- Reduced systemic microvascular function in patients with resistant hypertension and microalbuminuria: an observational study.Journal of human hypertension · 2024Observational
- Correlation of renal function indicators and vascular damage in T2DM patients with normal renal function.Frontiers in endocrinology · 2023Article
- Sonographic evaluation of hypertension: Role of atrophic index and renal resistive index.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- [Renal sympathetic denervation can significantly reduce blood pressure and improve arterial stiffness in hypertensive beagles].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Relationship of choroidal thickness with pulsatile hemodynamics in essential hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Association of renal resistance index and arterial stiffness on clinical outcomes in patients with mild-to-moderate renal dysfunction and presence or absence of heart failure with preserved ejection fraction.Heart and vessels · 2020Observational
- Relationship between arterial stiffness and chronic kidney disease in patients with primary hypertension.Journal of human hypertension · 2020Article
- Renal resistive index: Beyond the hemodynamics.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Vascular, cardiac and renal target organ damage associated to arterial hypertension: which noninvasive tools for detection?Journal of human hypertension · 2020Review
- Choroidal thickness is associated with renal hemodynamics in essential hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
- Renal haemodynamics and coronary atherosclerotic burden are associated in patients with hypertension and mild coronary artery disease.Experimental and therapeutic medicine · 2019Article
- Microalbuminuria and cardiorenal risk: old and new evidence in different populations.F1000Research · 2019Review
- Glycated hemoglobin correlates with arterial stiffness and endothelial dysfunction in patients with resistant hypertension and uncontrolled diabetes mellitus.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Association of renal systolic time intervals with brachial-ankle pulse wave velocity.International journal of medical sciences · 2018Observational
- Relationship between kidney findings and systemic vascular damage in elderly hypertensive patients without overt cardiovascular disease.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- Causes of changes in carotid intima-media thickness: a literature review.Cardiovascular ultrasound · 2015Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStructural atherosclerotic damage, arterial stiffness, pulse pressure (PP), and renal hemodynamics may interact and influence each other. Renal resistance index (RRI) appears as a good indicator of systemic vascular changes. The aim of our study was to assess the independent relationships of carotid intima-media thickness (cIMT), aortic pulse wave velocity (aPWV), and peripheral PP with RRI in hypertensives with various degrees of renal function.
methodsWe enrolled 463 hypertensive patients (30-70 years) with normal renal function (group 0; n = 280) and with chronic kidney disease (groups I-V; n = 183). All subjects underwent ultrasonographic examination of intrarenal and carotid vasculature, as well as a 24-h ambulatory blood pressure monitoring.
resultsA statistically significant difference in RRI, cIMT, aPWV, and clinic PP was observed in the different 6 groups (all P < 0.001), even after adjustment for age. RRI correlated with cIMT (r = 0.460, P < 0.001), aPWV (r = 0.386, P < 0.001), clinic PP (r = 0.279, P < 0.001), and 24-h PP (r = 0.229, P < 0.001) in the entire study population. These correlations were similar in subjects with and without renal dysfunction. In the overall study population, the association between RRI, cIMT, and clinic PP remained statistically significant even after adjustment for various confounding factors, whereas the relationship between RRI and aPWV was lost in multivariate analysis.
conclusionscIMT and clinic PP rather than directly aPWV are associated with intrarenal hemodynamics. Our results confirm that in hypertensives RRI not only detects derangement of intrarenal circulation but may also be considered as a sensor of systemic vascular changes, independently of level of renal function.
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