Evidence map›Paper›PMID 26232199›Full record

ArticlePharmacoEconomics2015

Valuing QALYs in Relation to Equity Considerations Using a Discrete Choice Experiment.

Liesbet van de Wetering, Job van Exel, Ana Bobinac, Werner B F Brouwer

Abstract read
In one paragraph

Article in PharmacoEconomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  5. Willingness to pay for a quality-adjusted life year: a systematic review with meta-regression.The European journal of health economics : HEPAC : health economics in prevention and care · 2022
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  10. The value of health and well-being from a societal perspective: A willingness to pay experiment in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
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  18. When is it too expensive? Cost-effectiveness thresholds and health care decision-making.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liesbet van de WeteringInstitute of Health Policy and Management, Erasmus University Rotterdam, 3000 DR, Rotterdam, The Netherlands. vandewetering@bmg.eur.nl.
Job van ExelInstitute of Health Policy and Management, Erasmus University Rotterdam, 3000 DR, Rotterdam, The Netherlands.
Ana BobinacInstitute of Health Policy and Management, Erasmus University Rotterdam, 3000 DR, Rotterdam, The Netherlands.
Werner B F BrouwerInstitute of Health Policy and Management, Erasmus University Rotterdam, 3000 DR, Rotterdam, The Netherlands. brouwer@bmg.eur.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo judge whether an intervention offers value for money, the incremental costs per gained quality-adjusted life-year (QALY) need to be compared with some relevant threshold, which ideally reflects the monetary value of health gains. Literature suggests that this value may depend on the equity context in which health gains are produced, but the value of a QALY in relation to equity considerations has remained largely unexplored.

objectiveThe objective of this study was to estimate the social marginal willingness to pay (MWTP) for QALY gains in different equity subgroups, using a discrete choice experiment (DCE). Both severity of illness (operationalized as proportional shortfall) and fair innings (operationalized as age) were considered as grounds for differentiating the value of health gains.

methodsWe obtained a sample of 1205 respondents, representative of the adult population of the Netherlands. The data was analysed using panel mixed multinomial logit (MMNL) and latent class models.

resultsThe panel MMNL models showed counterintuitive results, with more severe health states reducing the probability of receiving treatment. The latent class models revealed distinct preference patterns in the data. MWTP per QALY was sensitive to severity of disease among a substantial proportion of the public, but not to the age of care recipients.

conclusionThese findings emphasize the importance of accounting for preference heterogeneity among the public on value-laden issues such as prioritizing health care, both in research and decision making. This study emphasises the need to further explore the monetary value of a QALY in relation to equity considerations.

Indexed as

Choice BehaviorCost-Benefit AnalysisModels, EconomicQuality-Adjusted Life YearsDelivery of Health CareDiseaseHumansNetherlandsSeverity of Illness Index

Identifiers

PMID26232199
PMCPMC4661217

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.