Evidence map›Paper›PMID 26232125›Full record

ArticleMycopathologia2015

Paracoccidioides brasiliensis Infection in Small Wild Mammals.

Mônica Raquel Sbeghen, Thais Bastos Zanata, Rafaela Macagnan, Kaue Cachuba de Abreu, Willian Luiz da Cunha, Maria Angelica Ehara Watanabe, Zoilo Pires de Camargo, Mario Augusto Ono

Abstract read
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In one paragraph

Article in Mycopathologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Telomeric assemblies ofbioRxiv : the preprint server for biology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. New Trends in Paracoccidioidomycosis Epidemiology.Journal of fungi (Basel, Switzerland) · 2017
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Mônica Raquel SbeghenDepartamento de Ciências Patológicas, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Campus Universitário, Londrina, Paraná, 86057-970, Brazil.
Thais Bastos ZanataDepartamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Rafaela MacagnanDepartamento de Ciências Patológicas, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Campus Universitário, Londrina, Paraná, 86057-970, Brazil.
Kaue Cachuba de AbreuDepartamento de Zoologia, Universidade Federal do Paraná, Curitiba, Paraná, Brazil.
Willian Luiz da CunhaReserva Particular do Patrimônio Natural Monte Sinai, Mauá da Serra, Paraná, Brazil.
Maria Angelica Ehara WatanabeDepartamento de Ciências Patológicas, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Campus Universitário, Londrina, Paraná, 86057-970, Brazil.
Zoilo Pires de CamargoDisciplina de Biologia Celular, Universidade Federal de São Paulo, São Paulo, Brazil.
Mario Augusto OnoDepartamento de Ciências Patológicas, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Campus Universitário, Londrina, Paraná, 86057-970, Brazil. marioono@uel.br.
Universidade Estadual de Londrina · BRUniversidade Federal do Paraná · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paracoccidioidomycosis (PCM) is a systemic mycosis prevalent in Brazil and other Latin American countries. The etiological agents of PCM are the thermo-dimorphic fungi Paracoccidioides brasiliensis and P. lutzii. Taking into account that the natural habitat of Paracoccidioides spp. is still undefined, domestic and wild animals could be useful as indicators of Paracoccidioides spp. presence in endemic areas. The objective of this study was to evaluate the infection of small wild mammals by P. brasiliensis in an endemic area for human PCM. Samples from 38 wild mammals from different species such as Akodon sp., Thaptomys nigrita, Euryoryzomys russatus, Oligoryzomys nigripes, Monodelphis sp., Sooretamys angouya, Abrawayaomys angouya, Abrawayaomys ruschii and Akodontinae sp. were evaluated by ELISA, immunodiffusion, histopathology, nested PCR and culture. The overall positivity to gp43 observed in the ELISA was 23.7%. Samples from heart and liver of one O. nigripes were PCR positive, and the animal was also seropositive to gp43 in ELISA. This study showed that wild animals living in endemic areas for PCM are infected with P. brasiliensis and can be valuable epidemiological markers of the fungus presence in the environment. This is the first evidence of PCM infection in Akodon sp., E. russatus, T. nigrita and O. nigripes.

Indexed as

MonodelphisSigmodontinaeAnimalsAntibodies, FungalBrazilDNA, FungalEnzyme-Linked Immunosorbent AssayHeartLiverParacoccidioidesParacoccidioidomycosisPolymerase Chain ReactionPrevalenceAntibodies, FungalDNA, FungalELISAEpidemiologyParacoccidioidomycosisWild animals

Identifiers

PMID26232125
OpenAlexW1067738184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.