Evidence map›Paper›PMID 26232036›Full record

ArticleAmerican journal of hypertension2016

Repeatability of Central and Peripheral Pulse Wave Velocity Measures: The Atherosclerosis Risk in Communities (ARIC) Study.

Michelle L Meyer, Hirofumi Tanaka, Priya Palta, Mehul D Patel, Ricky Camplain, David Couper, Susan Cheng, Ada Al Qunaibet, Anna K Poon, Gerardo Heiss

Abstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  17. Association of central arterial stiffness with atrial myopathy: the Atherosclerosis Risk in Communities (ARIC) study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Michelle L MeyerDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; mlmeyer@unc.edu.
Hirofumi TanakaDepartment of Kinesiology and Health Education, University of Texas at Austin, Austin, Texas, USA;
Priya PaltaDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
Mehul D PatelCenter for Observational and Real World Evidence, Merck & Co., Inc, North Wales, Pennsylvania, USA;
Ricky CamplainDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
David CouperDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
Susan ChengCardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Ada Al QunaibetDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
Anna K PoonDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;
Gerardo HeissDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA;

Funding

Cardiovascular Epidemiology Training GrantT32HL007055 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Wayne D. Rosamond · 1986 to 2026
$10.0M
Myocardial and Arterial Aging: Spectrum, Correlates, and PrognosisR00HL107642 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CHENG, SUSAN · 2014 to 2016
$747k
NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012CNHLBI NIH HHS R00 HL107642NHLBI NIH HHS R00HL107642NHLBI NIH HHS T32 HL-007055NHLBI NIH HHS T32 HL007055PHS HHS HHSN268201100005CPHS HHS HHSN268201100006CPHS HHS HHSN268201100007CPHS HHS HHSN268201100008CPHS HHS HHSN268201100009CPHS HHS HHSN268201100010CPHS HHS HHSN268201100011CPHS HHS HHSN268201100012C
6 · The paper itself

Abstract

backgroundArterial stiffness measures are emerging tools for risk assessment and stratification for hypertension and cardiovascular disease (CVD). Carotid-femoral pulse wave velocity (cfPWV) is an established measure of central arterial stiffness. Other measures of PWV include femoral-ankle (faPWV), a measure of peripheral stiffness, and brachial-ankle PWV (baPWV), a composite measure of central and peripheral stiffness. Repeatability of central, peripheral, and composite PWV measures has not been adequately examined or compared.

methodsParticipants (n = 79; mean age 75.7 years; USA) from a repeatability study nested within the Atherosclerosis Risk in Communities (ARIC) Study visit 5 (2011-2013) underwent 2 standardized visits, 4-8 weeks apart. Trained technicians obtained 2 PWV measurements at each visit using the VP-1000 Plus system. We calculated the intraclass correlation coefficient (ICC), SE of measurement, and minimal detectable change (MDC95; 95% confidence interval) and difference (MDD).

resultsThe ICCs and 95% confidence intervals (95% CIs) were 0.70 (0.59, 0.81) for cfPWV, 0.84 (0.78, 0.90) for baPWV, and 0.69 (0.59, 0.79) for faPWV. The MDC95 between repeat measures within an individual was 411.0 cm/s for cfPWV, 370.6 cm/s for baPWV, and 301.4 cm/s for faPWV. The MDD for 2 independent samples of 100 per group was 139.3 cm/s for cfPWV, 172.3 cm/s for baPWV, and 100.4 cm/s for faPWV.

conclusionsRepeatability was acceptable for all PWV measures in a multicenter, population-based study of older adults and supports its use in epidemiologic studies. Quantifying PWV measurement variation is critical for applications to risk assessment and stratification and eventual translation to clinical practice.

Indexed as

Vascular StiffnessAgedAnkle Brachial IndexArterial PressureArteriesCardiovascular DiseasesFemaleHumansMaleObserver VariationPredictive Value of TestsPrognosisPulsatile FlowPulse Wave AnalysisReproducibility of ResultsRisk Assessmentarterial stiffnessblood pressurecentral arterial stiffnesshypertensionperipheral arterial stiffnessreliabilityreproducibilitysubclinical cardiovascular disease.

Identifiers

PMID26232036
PMCPMC4850900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.